Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment

ABSTRACT Human metapneumovirus (hMPV) is a respiratory virus with a significant impact, particularly on the paediatric population, yet it remains an under‐recognized contributor to respiratory infections globally. Recent epidemics in China, India and Europe underscore its clinical burden, with sever...

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發表在:Public Health Challenges
Main Authors: Victor Abiola Adepoju, Qorinah Estiningtyas Sakilah Adnani, Safayet Jamil, Masoud Mohammadnezhad, Abdulrakib Abdulrahim
格式: Article
語言:英语
出版: Wiley 2025-09-01
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在線閱讀:https://doi.org/10.1002/puh2.70094
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author Victor Abiola Adepoju
Qorinah Estiningtyas Sakilah Adnani
Safayet Jamil
Masoud Mohammadnezhad
Abdulrakib Abdulrahim
author_facet Victor Abiola Adepoju
Qorinah Estiningtyas Sakilah Adnani
Safayet Jamil
Masoud Mohammadnezhad
Abdulrakib Abdulrahim
author_sort Victor Abiola Adepoju
collection DOAJ
container_title Public Health Challenges
description ABSTRACT Human metapneumovirus (hMPV) is a respiratory virus with a significant impact, particularly on the paediatric population, yet it remains an under‐recognized contributor to respiratory infections globally. Recent epidemics in China, India and Europe underscore its clinical burden, with severe cases linked to bronchiolitis, pneumonia and exacerbations of chronic conditions. Despite its impact, hMPV remains underdiagnosed due to limited access to molecular diagnostics and routine surveillance, particularly in low‐ and middle‐income countries. The absence of antivirals or vaccines exacerbates its public health challenge. Advances in multiplex diagnostics and vaccine development offer hope but require sustained global investment. Addressing gaps in prevention, diagnostics and treatment is critical to mitigating hMPV's growing threat and ensuring equitable healthcare outcomes.
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spelling doaj-art-b052d1ca112343ef979ce682306c60d32025-09-23T12:41:05ZengWileyPublic Health Challenges2769-24502025-09-0143n/an/a10.1002/puh2.70094Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and TreatmentVictor Abiola Adepoju0Qorinah Estiningtyas Sakilah Adnani1Safayet Jamil2Masoud Mohammadnezhad3Abdulrakib Abdulrahim4Department of HIV and Infectious Diseases Jhpiego, An Affiliate of John Hopkins University Abuja NigeriaDepartment of Public Health Faculty of Medicine, Universitas Padjadjaran Bandung West Java IndonesiaDepartment of Public and Community Health Faculty of Medicine and Health Sciences, Frontier University Garowe Puntland SomaliaFaculty of Health, Education and Life SciencesBirmingham City UniversityBirmingham United KingdomDepartment of Medical Microbiology Faculty of Medicine and Health Sciences Universiti Putra Malaysia Serdang Selangor MalaysiaABSTRACT Human metapneumovirus (hMPV) is a respiratory virus with a significant impact, particularly on the paediatric population, yet it remains an under‐recognized contributor to respiratory infections globally. Recent epidemics in China, India and Europe underscore its clinical burden, with severe cases linked to bronchiolitis, pneumonia and exacerbations of chronic conditions. Despite its impact, hMPV remains underdiagnosed due to limited access to molecular diagnostics and routine surveillance, particularly in low‐ and middle‐income countries. The absence of antivirals or vaccines exacerbates its public health challenge. Advances in multiplex diagnostics and vaccine development offer hope but require sustained global investment. Addressing gaps in prevention, diagnostics and treatment is critical to mitigating hMPV's growing threat and ensuring equitable healthcare outcomes.https://doi.org/10.1002/puh2.70094global health | human metapneumovirus (hMPV) | respiratory virus | viral pneumonia
spellingShingle Victor Abiola Adepoju
Qorinah Estiningtyas Sakilah Adnani
Safayet Jamil
Masoud Mohammadnezhad
Abdulrakib Abdulrahim
Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
global health | human metapneumovirus (hMPV) | respiratory virus | viral pneumonia
title Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
title_full Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
title_fullStr Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
title_full_unstemmed Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
title_short Global Burden of Human Metapneumovirus: Bridging Gaps in Prevention, Diagnostics and Treatment
title_sort global burden of human metapneumovirus bridging gaps in prevention diagnostics and treatment
topic global health | human metapneumovirus (hMPV) | respiratory virus | viral pneumonia
url https://doi.org/10.1002/puh2.70094
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