Notes on human cases of cystic echinococcosis in Peru

Cystic echinococcosis (CE) is a high prevalent zoonosis in the central and southern Peruvian Andes. Serum samples (n50)frompatients presenting presumptive clinical and radiological diagnosis of CE (group 1), were tested for antibodies against Echinococcus granulosus metacestode using Arc-5 double di...

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Bibliographic Details
Published in:Memorias do Instituto Oswaldo Cruz
Main Authors: Elizabeth Luz Sanchez Romani, Rosângela Rodrigues-Silva, Arnaldo Maldonado Jr., José Roberto Machado-Silva, Delir Corrêa Gomes
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2006-05-01
Subjects:
Echinococcus granulosus
cystic echinococcosis
human cases
Peru
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000300020
Description
Summary:Cystic echinococcosis (CE) is a high prevalent zoonosis in the central and southern Peruvian Andes. Serum samples (n50)frompatients presenting presumptive clinical and radiological diagnosis of CE (group 1), were tested for antibodies against Echinococcus granulosus metacestode using Arc-5 double diffusion assay (DD5), immunoelectrophoresis (IEF), and immunoelectrotransfer blot (EITB) techniques. Serum samples (n18) from patients presenting other parasite infections (paragonomiasis, cysticercosis, and fascioliasis) or healthy blood donors (n15), were designated as control groups. The overall sensitivity of the tests was of 94% (DD5 and IEF tests) or 96% (EITB test). Only patients from group 1 were seropositive for CE. Polypeptides of 21, 31, and 48 kDa were considered positive for CE. Based on these results, this study demonstrates that CE also occurs in other coastal departments (Piura, Ancash, Ica, Arequipa, and Tacna) besides Lima.
ISSN:0074-0276
1678-8060

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