Comparison of Stimdate with Ritalin in Children and Adolescents with Attention Deficit Hyperactivity Disorder: a Double-Blind, Randomized Clinical Trial

• Published in: Iranian Journal of Psychiatry
• Main Authors: Najmeh Khosrovan Mehr, Shahin Akhondzadeh, Mohammad Reza Mohammadi, Mohammad Mohammadi, Somayeh Mahintorabi
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2009-02-01
• Subjects: Attention Deficit Hyperactivity Disorder (ADHD); adolescents; children; methylphenidate; Ritalin; Stimdate
• Online Access: http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14188.pdf&manuscript_id=14188
• ISSN: 1735-4587; 2008-2215

"nObjectives: The aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (ADHD). "nMethod: Sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with ADHD based on (DSM-IV-TR) criteria were selected for this study. The subjects were randomly assigned to two groups: one group with 30 subjects received stimdate and the other group of 30 subjects received ritalin for 6 weeks. Treatment outcomes were assessed using the Attention Deficit Hyperactivity Rating Scale administered at baseline and on weeks 2, 4 and 6 following the treatment. A two-way repeated measures analysis of variance (time- treatment interaction) was used. "nResults: There were no significant differences between sex, age, weight, and ethnicity of the participants in the 2 groups. Both groups showed a significant improvement during the 6 weeks of the treatment period, and this improvement was due to the parents' ADHD Rating Scale during the treatment. "nConclusion: Based on the results of this study, no significant difference was observed between the two medications, and it seems both drugs behave[M1]  in a similar way. In addition, stimdate appears to be effective and well tolerated for ADHD in children and adolescents in Iran. "n