Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway

IntroductionMiR-144-5p is differentially expressed in plasma exosomes from Bactrian camels of varying body sizes, with GO and KEGG analyses indicating that its target genes play crucial roles in lipid metabolism. PGC-1α, confirmed as a key target through RNA pull-down and dual-luciferase reporter as...

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Bibliographic Details
Published in:	Frontiers in Veterinary Science
Main Authors:	Siriguleng Yu, Chaoqun Liu, Hong Lv, Zhijun Guo, Hongqiang Yao, Xin Wen, Ying Xiu, Wa Gao, Ziyi Li, Wen Yu, Yaru Niu, Junjian Jin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	Bactrian camel exosome metabolism miR-144-5p PGC-1α
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1477593/full

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