N-Heterocyclic carbene-catalyzed enantioselective synthesis of planar-chiral cyclophanes via dynamic kinetic resolution

Abstract Planar-chiral cyclophanes have gained considerable concerns for drug discovery due to their unique conformational strain and 3D structure. However, the enantioselective synthesis of planar-chiral cyclophanes is a long-standing challenge for the synthetic community. We herein describe an N-h...

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Bibliographic Details
Published in:	Nature Communications
Main Authors:	Jiayan Li, Ziyang Dong, Yang Chen, Zhanhui Yang, Xinen Yan, Meng Wang, Chenyang Li, Changgui Zhao
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-03-01
Online Access:	https://doi.org/10.1038/s41467-024-46376-8

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