Myocyte Enhancer Factor 2A Contributes to the TGF-β1-Mediated Cholangiocyte Epithelial to Mesenchymal Transition and Senescence in Cholestatic Liver Fibrosis

Background: Cholangiocytes are primary targets in chronic cholestatic liver diseases. Myocyte enhancer factor 2A (MEF2A) is a transcription factor with a crucial role in some fibrogenic diseases. However, whether it contributes to cholestatic liver fibrosis is still obscure. Methods: A bile duct–lig...

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Bibliographic Details
Published in:	Frontiers in Bioscience-Landmark
Main Authors:	Guangxi Zhou, Fei Hou, Heng He, Yuan Xue, Yibo Wang, Xueying Chen, Fengqin Zhu
Format:	Article
Language:	English
Published:	IMR Press 2022-12-01
Subjects:	mef2a emt senescence fibrosis cholangiocytes
Online Access:	https://www.imrpress.com/journal/FBL/27/12/10.31083/j.fbl2712324

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