Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Abstract Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling...

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書誌詳細

出版年:	Genome Biology
主要な著者:	Raphaël Mourad, Krzysztof Ginalski, Gaëlle Legube, Olivier Cuvier
フォーマット:	論文
言語:	英語
出版事項:	BMC 2018-03-01
主題:	Double-strand breaks Epigenetics Chromatin Machine learning
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13059-018-1411-7