Molecular Detection of Multiple Antimicrobial Resistance Genes in <i>Helicobacter pylori</i>-Positive Gastric Samples from Patients Undergoing Upper Gastrointestinal Endoscopy with Gastric Biopsy in Algarve, Portugal

<b>Background/Objectives</b>: <i>Helicobacter pylori</i> (<i>H. pylori</i>) is a common gastric pathogen linked to gastritis, gastroduodenal ulcers, and gastric cancer. Rising antimicrobial resistance (AMR) poses challenges for effective treatment and has prompted...

Full description

Bibliographic Details
Published in:	Antibiotics
Main Authors:	Francisco Cortez Nunes, Catarina Aguieiras, Mauro Calhindro, Ricardo Louro, Bruno Peixe, Patrícia Queirós, Pedro Castelo-Branco, Teresa Letra Mateus
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	metronidazole tetracycline PCR sequencing AMR
Online Access:	https://www.mdpi.com/2079-6382/14/8/780

Similar Items

Prevalence and Diagnostic Comparison of <i>Helicobacter pylori</i> and Non-<i>Helicobacter pylori Helicobacter</i> Infections in Patients Undergoing Upper Gastrointestinal Endoscopy with Gastric Biopsy in Algarve, Portugal
by: Francisco Cortez Nunes, et al.
Published: (2025-07-01)

Trends of antibiotic resistance of Helicobacter pylori in Moscow
by: Igor V. Maev, et al.
Published: (2025-01-01)

Antibiotic Resistance Prevalence and Trends in Patients Infected with <i>Helicobacter pylori</i> in the Period 2013–2020: Results of the European Registry on <i>H. pylori</i> Management (Hp-EuReg)
by: Luis Bujanda, et al.
Published: (2021-09-01)

Antimicrobial resistance of Helicobacter pylori strains to five antibiotics, including levofloxacin, in Northwestern Turkey
by: Reyhan Caliskan, et al.
Published: (2015-06-01)

Detection of <i>Helicobacter pylori</i> and the Genotypes of Resistance to Clarithromycin, Fluoroquinolones, and Metronidazole in Gastric Biopsies: An In Silico Analysis to Help Understand Antibiotic Resistance
by: Pedro Valada, et al.
Published: (2025-03-01)

A new approach to the treatment of acute infection diseases with antibiotic-pectin formulae
by: Zayniddin K Muhidinov, et al.
Published: (2024-03-01)

Сlinical and molecular aspects of helicobacter pylori resistance to antimicrobial drugs
by: Y. A. Kucheryaviy, et al.
Published: (2013-12-01)

RdxA-independent mechanism of Helicobacter pylori metronidazole metabolism
by: Yakun Zhao, et al.
Published: (2025-03-01)

Molecular Detection of Metronidazole and Tetracycline Resistance Genes in <i>Helicobacter pylori</i>-Like Positive Gastric Samples from Pigs
by: Francisco Cortez Nunes, et al.
Published: (2023-05-01)

Effect of Temperature on Metronidazole Resistance in Helicobacter pylori
by: Meiliang Gong, et al.
Published: (2021-05-01)

Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for Helicobacter pylori Infection
by: Jae Hyun Jung, et al.
Published: (2018-03-01)

Transitioning of <i>Helicobacter pylori</i> Therapy from Trial and Error to Antimicrobial Stewardship
by: David Y. Graham
Published: (2020-10-01)

Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran
by: Farzad Khademi, et al.
Published: (2013-01-01)

Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury
by: Carina Silva, et al.
Published: (2023-11-01)

Characterization and Antimicrobial Susceptibility of Pathogens Associated with Periodontal Abscess
by: Muhammad Irshad, et al.
Published: (2020-09-01)

Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam
by: Vu Van Khien, et al.
Published: (2019-09-01)

Ten-day tegoprazan-based concomitant therapy as a first-line treatment for Helicobacter pylori eradication
by: Yong Hwan Kwon, et al.
Published: (2023-07-01)

Susceptibility testing of Helicobacter pylori: Comparison of E-test and Disk Diffusion for Metronidazole and Mutations in rdxA gene sequences of Helicobacter pylori strains
by: Laleh Mahmoudi, et al.
Published: (2015-12-01)

Biological Cost of Helicobacter pylori Rifampicin Resistance
by: K. T. Momynaliev, et al.
Published: (2020-05-01)

Assessment of the feasibility of the formulation of preparation for the growth inhibition of metronidazole-resistant strains isolated from the periodontal pockets
by: Toskić-Radojičić Marija, et al.
Published: (2005-01-01)

The mutation of the rdxA gene in metronidazole-resistant Helicobacter pylori clinical isolates
by: Nasrin Mirzaei, et al.
Published: (2014-01-01)

Assessing the role of the RND efflux pump in metronidazole resistance of Helicobacter pylori by RT-PCR assay
by: Jalil Fallah Mehrabadi, et al.
Published: (2010-10-01)

Comparison of amoxicillin and metronidazole effect on three-drug regimen for the treatment of Helicobacter pylori infection in children
by: Karam-Ali Kasiri, et al.
Published: (2017-01-01)

Primary Antibiotic Resistance of <i>Helicobacter pylori</i> in Different Regions of China: A Systematic Review and Meta-Analysis
by: Jinnan Chen, et al.
Published: (2022-07-01)

Phenotypic and Genotypic Analysis of Resistant <i>Helicobacter pylori</i> Strains Isolated from Children with Gastrointestinal Diseases
by: Monika Maria Biernat, et al.
Published: (2020-09-01)

Efficiency of Diagnostic Testing for <i>Helicobacter pylori</i> Infections—A Systematic Review
by: Paula Rojas García, et al.
Published: (2021-01-01)

Impact of previous metronidazole exposure on metronidazole-based second-line quadruple therapy for Helicobacter pylori infection
by: Gil Ho Lee, et al.
Published: (2020-09-01)

Surveillance of Helicobacter pylori resistance over 22 Years (2000-2021) in Northern Spain
by: Marta Gómez-Ruiz de Arbulo, et al.
Published: (2023-09-01)

Molecular and proteomic analysis of levofloxacin and metronidazole resistant Helicobacter pylori
by: Aimi Hanafi, et al.
Published: (2016-12-01)

45 years of tetracycline post exposure prophylaxis for STIs and the risk of tetracycline resistance: a systematic review and meta-analysis
by: Thibaut Vanbaelen, et al.
Published: (2024-04-01)

Determinants of resistance to levofloxacin and metronidazole in Russian clinical isolates of <i>Helicobacter pylori</i> based on whole-genome sequencing data
by: Daria А. Starkova, et al.
Published: (2025-09-01)

Carbon dot based molecularly imprinted polymer for selective fluorometric determination of tetracycline and metronidazole in pharmaceuticals and human plasma
by: Khadiga M. Kelani, et al.
Published: (2025-08-01)

Exploring the Link between <i>Helicobacter pylori</i>, Gastric Microbiota and Gastric Cancer
by: Costantino Sgamato, et al.
Published: (2024-05-01)

Levofloxacin, Metronidazole, and Lansoprazole Triple Therapy Compared to Quadruple Therapy as a Second-Line Treatment of Helicobacter pylori Infection in Korea
Published: (2013-07-01)

Molecular Detection of Tetracycline-Resistant Genes in Multi-Drug-Resistant <i>Escherichia coli</i> Isolated from Broiler Meat in Bangladesh
by: Gazi Sofiul Alam, et al.
Published: (2023-02-01)

<i>Helicobacter pylori</i> and Its Role in Gastric Cancer
by: Victor E. Reyes
Published: (2023-05-01)

Optimal First-line Eradication Regimens for Helicobacter pylori Infection in Patients with Clarithromycin Resistance: A Pilot Study
by: Min Woo Seo, et al.
Published: (2018-12-01)

Amoxicillin or tetracycline in bismuth-containing quadruple therapy as first-line treatment for Helicobacter pylori infection
by: Chang Seok Bang, et al.
Published: (2020-09-01)

Comparison of azithromycin and metronidazole in a quadruple-therapy regimen for <i>Helicobacter pylori</i> eradication in dyspepsia
by: Agah Shahram, et al.
Published: (2009-01-01)

High Primary Antibiotic Resistance of <i>Helicobacter pylori</i> Strains Isolated from Pediatric and Adult Patients in Poland during 2016–2018
by: Paweł Krzyżek, et al.
Published: (2020-05-01)