Risk stratification and contributing factors of deep vein thrombosis among patients admitted at Debre Markos comprehensive specialized hospital, Ethiopia in 2024

• Published in: Frontiers in Medicine
• Main Authors: Haymanot Zeleke Mitiku, Birtukan Assefa Addis, Afework Edmealem, Dejen Tsegaye, Yalemgeta Biyazin, Abebe Abate
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2024-12-01
• Subjects: prevalence; stratification; deep vein thrombosis; Wells Clinical Prediction Model; Ethiopia
• Online Access: https://www.frontiersin.org/articles/10.3389/fmed.2024.1470212/full

IntroductionDeep vein thrombosis is a serious condition and a leading cause of morbidity and mortality in hospitalized patients. Studies conducted in various hospitals in Ethiopia have reported that the prevalence rates of deep vein thrombosis range from approximately 5–10% among hospitalized patients. The risk stratification of deep vein thrombosis and the identification of associated risk factors are critical for assessing deep vein thrombosis in hospital settings. Wells scoring provides a valuable framework for assessing individual risk. This study aims to assess the risk stratification of deep vein thrombosis and to identify the risk factors among patients admitted at Debre Markos Comprehensive Specialized Hospital.MethodA facility-based cross-sectional study was conducted from December 2023 to February 2024. The study included 423 adult patients, and the data were collected using a structured questionnaire and chart review. Ordinal logistic regression analysis was conducted after performing the model test.ResultThe prevalence of deep vein thrombosis was found to be 7.9%, with 44.2% categorized as having no risk, 8.1% as moderate risk, and 47.7% as high risk for deep vein thrombosis stratification. Various risk factors, such as regular alcohol consumption (odd ratio 4.59, p = 0.032), a previous history of deep vein thrombosis (odd ratio 28.32, p = 0.000), the presence of a central catheter (odd ratio 12.92, p = 0.000), a severe lipid profile (odd ratio 3.8, p = 0.001), and a longer duration of stay in the ward (odd ratio 1.28, p = 0.000), were significantly associated with high risk for deep vein thrombosis stratification.ConclusionThe prevalence of high-risk deep vein thrombosis stratification was found to be high, and the occurrence of deep vein thrombosis was also high within this risk group. Regular alcohol consumption, a previous history of deep vein thrombosis, the presence of a central catheter, a severe lipid profile, and a longer duration of stay in the ward were statistically significant for high-risk deep vein thrombosis stratification. This study highlights the importance of identifying patients who are at high risk for deep vein thrombosis stratification and addressing the risk factors for deep vein thrombosis stratification.