Harnessing exercise to combat chronic diseases: the role of Drp1-Mediated mitochondrial fission

Enhanced Drp1 activity mediates excessive mitochondrial fission, contributing to the onset and progression of various chronic diseases, including neurodegenerative, cardiovascular, and metabolic disorders. Studies indicate that exercise mitigates mitochondrial dysfunction by modulating Drp1-related...

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Bibliographic Details
Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Yingxin Sun, Junchen He, Lei Bao, Xiaoming Shi, Jinghong Wang, Qingwen Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	physical exercise mitochondrial fission Drp1 chronic diseases mechanism
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1481756/full

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