Identification and clinical transfusion of B (A) subgroup

• Published in: Zhongguo shuxue zazhi
• Main Authors: Jun MIAO, Minglu GENG, Janbin LI, Xiaoli MA, Hecai YANG, Liping WANG, Dan LIU, Ke ZHANG, Chuan ZHOU, Junjie CHENG
• Format: Article
• Language: Chinese
• Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2023-11-01
• Subjects: abo blood group; b(a) subgroup; blood group identification; cross matching
• Online Access: https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2023.11.009&lang=en
• ISSN: 1004-549X

Objective To carry out serological and molecular biological identification of B (A) subtype, and discuss the rational blood transfusion strategy. Methods Serological and direct sequencing methods were used to detect serotype and genotype of 7 cases of B (A) subtype, and cross matching was performed by saline medium and anti human globulin card to analyze the red blood cells(RBCs) transfusion strategy. Results The serology results of blood type of 7 samples were similar, with B(A)04/O01 in 3 cases, B(A)04/O02 in 2 cases and B(A)02/O01 in 2 cases. 7 cases of B (A) subtypes were matched with randomly selected blood donors of type O and B on the major side. Conclusion B(A) subtypes should be identified by genotyping techniques. Washed RBCs of type B and O can be used for B(A) blood type transfusion.