Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.

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Clinical studies report that viral infections promote acute or chronic bacterial infections at multiple host sites. These viral-bacterial co-infections are widely linked to more severe clinical outcomes. In experimental models in vitro and in vivo, virus-induced interferon responses can augment host...

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Published in:	PLoS Pathogens
Main Authors:	Grace P Carreno-Florez, Brian R Kocak, Matthew R Hendricks, Jeffrey A Melvin, Katrina B Mar, Jessica Kosanovich, Rachel L Cumberland, Greg M Delgoffe, Sruti Shiva, Kerry M Empey, John W Schoggins, Jennifer M Bomberger
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-11-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011719&type=printable

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection by Grace P. Carreno-Florez, Brian R. Kocak, Matthew R. Hendricks, Jeffrey A. Melvin, Katrina B. Mar, Jessica Kosanovich, Rachel L. Cumberland, Greg M. Delgoffe, Sruti Shiva, Kerry M. Empey, John W. Schoggins, Jennifer M. Bomberger

Published in PLoS Pathogens (2023-11-01)

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Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.

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