Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering
Many types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with...
| الحاوية / القاعدة: | Nanomaterials |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
MDPI AG
2020-12-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.mdpi.com/2079-4991/11/1/21 |
| _version_ | 1851832420987305984 |
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| author | Mina Keshvardoostchokami Sara Seidelin Majidi Peipei Huo Rajan Ramachandran Menglin Chen Bo Liu |
| author_facet | Mina Keshvardoostchokami Sara Seidelin Majidi Peipei Huo Rajan Ramachandran Menglin Chen Bo Liu |
| author_sort | Mina Keshvardoostchokami |
| collection | DOAJ |
| container_title | Nanomaterials |
| description | Many types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with other bioactive components could enable the engineering of microenvironments to host cells for regenerative medical applications. In the current brief review, we focus on the most recently cited electrospun nanofibrous polymeric scaffolds and divide them into five main categories: natural polymer-natural polymer composite, natural polymer-synthetic polymer composite, synthetic polymer-synthetic polymer composite, crosslinked polymers and reinforced polymers with inorganic materials. Then, we focus on their physiochemical, biological and mechanical features and discussed the capability and efficiency of the nanofibrous scaffolds to function as the extracellular matrix to support cellular function. |
| format | Article |
| id | doaj-art-bdfdb9fa42e44dcba6edcf0e188071c5 |
| institution | Directory of Open Access Journals |
| issn | 2079-4991 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-bdfdb9fa42e44dcba6edcf0e188071c52025-08-19T22:31:36ZengMDPI AGNanomaterials2079-49912020-12-011112110.3390/nano11010021Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue EngineeringMina Keshvardoostchokami0Sara Seidelin Majidi1Peipei Huo2Rajan Ramachandran3Menglin Chen4Bo Liu5Laboratory of Functional Molecules and Materials, School of Physics and Optoelectronic Engineering, Shandong University of Technology, Xincun West Road 266, Zibo 255000, ChinaInterdisciplinary Nanoscience Center (iNANO), Aarhus University, DK-8000 Aarhus C, DenmarkLaboratory of Functional Molecules and Materials, School of Physics and Optoelectronic Engineering, Shandong University of Technology, Xincun West Road 266, Zibo 255000, ChinaLaboratory of Functional Molecules and Materials, School of Physics and Optoelectronic Engineering, Shandong University of Technology, Xincun West Road 266, Zibo 255000, ChinaInterdisciplinary Nanoscience Center (iNANO), Aarhus University, DK-8000 Aarhus C, DenmarkLaboratory of Functional Molecules and Materials, School of Physics and Optoelectronic Engineering, Shandong University of Technology, Xincun West Road 266, Zibo 255000, ChinaMany types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with other bioactive components could enable the engineering of microenvironments to host cells for regenerative medical applications. In the current brief review, we focus on the most recently cited electrospun nanofibrous polymeric scaffolds and divide them into five main categories: natural polymer-natural polymer composite, natural polymer-synthetic polymer composite, synthetic polymer-synthetic polymer composite, crosslinked polymers and reinforced polymers with inorganic materials. Then, we focus on their physiochemical, biological and mechanical features and discussed the capability and efficiency of the nanofibrous scaffolds to function as the extracellular matrix to support cellular function.https://www.mdpi.com/2079-4991/11/1/21electrospinningscaffoldnanofibersextracellular matrixbioengineering |
| spellingShingle | Mina Keshvardoostchokami Sara Seidelin Majidi Peipei Huo Rajan Ramachandran Menglin Chen Bo Liu Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering electrospinning scaffold nanofibers extracellular matrix bioengineering |
| title | Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering |
| title_full | Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering |
| title_fullStr | Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering |
| title_full_unstemmed | Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering |
| title_short | Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering |
| title_sort | electrospun nanofibers of natural and synthetic polymers as artificial extracellular matrix for tissue engineering |
| topic | electrospinning scaffold nanofibers extracellular matrix bioengineering |
| url | https://www.mdpi.com/2079-4991/11/1/21 |
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