Status of KRAS in iPSCs Impacts upon Self-Renewal and Differentiation Propensity

Summary: Oncogenic KRAS mutations in hematopoietic stem cells cause RAS-associated autoimmune lymphoproliferative syndrome-like disease (RALD). KRAS plays essential roles in stemness maintenance in some types of stem cells. However, its roles in pluripotent stem cells (PSCs) are poorly understood. H...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Stem Cell Reports
المؤلفون الرئيسيون:	Kenji Kubara, Kazuto Yamazaki, Yasuharu Ishihara, Takuya Naruto, Huan-Ting Lin, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Masashi Ito, Kappei Tsukahara, Tomohiro Morio, Masatoshi Takagi, Makoto Otsu
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2018-08-01
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2213671118302716

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