Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation

Abstract Menthol has a considerable cooling effect, but the use range of menthol is limited because of its extremely low solubility in water and inherent flavor. (−)-Menthol β-glucoside was determined to be more soluble in water (>27 times) than (−)-menthol α-glucoside; hence, β-anomer-selective...

Full description

Bibliographic Details
Published in:	AMB Express
Main Authors:	Ha-Young Choi, Bo-Min Kim, Abubaker M. A. Morgan, Joong Su Kim, Won-Gon Kim
Format:	Article
Language:	English
Published:	SpringerOpen 2017-08-01
Subjects:	Menthol Menthol β-glycosides Glycosyltransferase Solubility Cooling
Online Access:	http://link.springer.com/article/10.1186/s13568-017-0468-0

Similar Items

Menthol and Its Derivatives: Exploring the Medical Application Potential
by: Jing Zhang, et al.
Published: (2025-09-01)

Menthol cigarette pricing at military and community retail outlets in the United States
by: Poston Walker SC, et al.
Published: (2012-09-01)

Smoking cessation prevalence by menthol cigarette use and select demographics among adults in the United States, TUS-CPS, 2003–2019
by: Jamal T. Jones, et al.
Published: (2023-12-01)

Comparison on menthol content of cultivated Peppermint at different regions of Iran
by: D Yazdani, et al.
Published: (2002-09-01)

Carbitol as adulterant in menthol; analytical method for quantitative analysis of adulteration
by: Indrajit Sen, et al.
Published: (2020-05-01)

Antiviral Effects of Menthol on Coxsackievirus B
by: David J.R. Taylor, et al.
Published: (2020-03-01)

Anti-leukemic effect of menthol, a peppermint compound, on induction of apoptosis and autophagy
by: Mashima Naksawat, et al.
Published: (2023-03-01)

Why menthol bans protect African Americans
by: Kelsey Romeo-Stuppy, et al.
Published: (2021-11-01)

Optimal fabrication of nano menthol/PEG particles by electrospraying
by: M Aali-Kordkolaei, et al.
Published: (2016-02-01)

Menthol and flavored tobacco products in LMICs: A growing menace
by: Mateusz Zatoński, et al.
Published: (2022-04-01)

Menthol mouth rinsing and performance in elite football referees in the heat: A study protocol for a randomized crossover trial
by: Maria Roriz, et al.
Published: (2023-10-01)

Comparative Cytotoxicity of Menthol and Eucalyptol: An In Vitro Study on Human Gingival Fibroblasts
by: Clara Puig-Herreros, et al.
Published: (2024-04-01)

Comparison of the effect of topical application of rosemary and menthol for musculoskeletal pain in hemodialysis patients
by: Sekine Keshavarzian, et al.
Published: (2017-01-01)

Thermal Triggered Release of Menthol from Different Carriers: A Comparative Study
by: Min Wei, et al.
Published: (2020-03-01)

Menthol-loaded PLGA Micro and Nanospheres: Synthesis, Characterization and Degradation in Artificial Saliva
by: Juliana Pelisoli Holz, et al.
Published: (2018-02-01)

Preformulation Studies of Novel Menthol Prodrugs with Antiparasitic Activity: Chemical Stability, In Silico, and In Vitro Permeability Assays
by: Camila M. Clemente, et al.
Published: (2023-09-01)

The health effects of menthol cigarettes as compared to non-menthol cigarettes
by: Allison C. Hoffman
Published: (2011-05-01)

The Development of a Menthol Solution for Use during Sport and Exercise
by: Russ Best, et al.
Published: (2018-06-01)

Menthol induces extracellular vesicle regulation of apoptosis via ATG3 and caspase-3 in acute leukemic cells
by: Kantorn Charoensedtasin, et al.
Published: (2024-06-01)

Synthesis of Water-Soluble Menthol Derivatives Using Response Surface Methodology
by: Shafaq Nisar, et al.
Published: (2024-12-01)

Tobacco use behaviors in response to menthol restriction: A scoping review
by: Esme E. Wright, et al.
Published: (2025-02-01)

L-Menthol-Loadable Electrospun Fibers of PMVEMA Anhydride for Topical Administration
by: Amalia Mira, et al.
Published: (2021-11-01)

Biocatalytic Acylation of Menthol with Fatty Acids in Deep Eutectic Solvent as Reaction Environment
by: Florentina Olanescu, et al.
Published: (2022-03-01)

Synthesis of liquid menthol by hydrogenation of dementholized peppermint oil over Ni catalysts
by: Debora L. Manuale, et al.
Published: (2010-01-01)

The Use of L-Menthol in Endoscopic Transpapillary Interventions. Prospective Randomized Dual-Center Study
by: M. A. Anishchenko, et al.
Published: (2023-12-01)

Ileum transcriptional response to prolonged supplementation with phytogenic product containing menthol, carvacrol and carvone
by: Yadav S. Bajagai, et al.
Published: (2022-03-01)

Menthol: An underestimated anticancer agent
by: Yijia Zhao, et al.
Published: (2023-03-01)

Anaesthetic profile of thymol and menthol in zebrafish larvae model
by: Raquel S.F. Vieira, et al.
Published: (2025-05-01)

Menthol facilitates the intravenous self-administration of nicotine in rats
by: Tengfei eWang, et al.
Published: (2014-12-01)

Antinociceptive Analysis of Natural Monoterpenes Eugenol, Menthol, Carvacrol and Thymol in a Zebrafish Larval Model
by: Cláudia Alexandra Rocha, et al.
Published: (2024-04-01)

Corrosion of ancient Chinese bronze fragments from different periods and protective effect of menthol coating
by: Tianliang Zhao, et al.
Published: (2023-12-01)

Dietary supplementation of menthol-rich bioactive lipid compounds alters circadian eating behaviour of sheep
by: Amlan K. Patra, et al.
Published: (2019-10-01)

Menthol carbonates as potent antiparasitic agents: synthesis and in vitro studies along with computer-aided approaches
by: Camila M. Clemente, et al.
Published: (2022-06-01)

Effects of cutaneous administration of an over-the-counter menthol cream during temperate-water immersion for exercise-induced hyperthermia in men
by: Gang Wang, et al.
Published: (2023-05-01)

Current Perspectives on Characteristics, Compositions, and Toxicological Effects of E-Cigarettes Containing Tobacco and Menthol/Mint Flavors
by: Gurjot Kaur, et al.
Published: (2020-11-01)

How Cool is That? The Effects of Menthol Mouth Rinsing on Exercise Capacity and Performance: A Systematic Review and Meta-analysis
by: Erica H. Gavel, et al.
Published: (2024-02-01)

The Effect of the Film Thickness, Cooling Rate, and Solvent Evaporation on the Formation of <i>L</i>-Menthol Ring-Banded Spherulites
by: Tamás Kovács, et al.
Published: (2024-12-01)

From Molecular Interactions to Solubility in Deep Eutectic Solvents: Exploring Flufenamic Acid in Choline-Chloride- and Menthol-Based Systems
by: Piotr Cysewski, et al.
Published: (2025-08-01)

Biochemical changes in rats after treatment with soft drink and menthol flavoured candy
by: E. F. Isoje, et al.
Published: (2025-04-01)

Phytohormonal elicitation triggers oxidative stress and enhances menthol biosynthesis through modulation of key pathway genes in Mentha piperita L.
by: Iman Khaldari, et al.
Published: (2025-08-01)