Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity
Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using...
| الحاوية / القاعدة: | Frontiers in Pediatrics |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Frontiers Media S.A.
2022-01-01
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.frontiersin.org/articles/10.3389/fped.2021.797684/full |
| _version_ | 1852709678469873664 |
|---|---|
| author | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Susan Ostmo Michael F. Chiang Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell |
| author_facet | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Susan Ostmo Michael F. Chiang Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell |
| author_sort | Thanh-Tin P. Nguyen |
| collection | DOAJ |
| container_title | Frontiers in Pediatrics |
| description | Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the operating room of Oregon Health & Science University (OHSU) Hospital. In this observational study, we provide an overview of potential advantages of OCT-based disease assessment in ROP. We observed that next-generation OCT imaging (a) may be sufficient for objective diagnosis and zone/stage/plus disease categorization, (b) allows for minimally-invasive longitudinal monitoring of disease progression and post-treatment course, (c) provides three-dimensional mapping of the vitreoretinal interface, and (d) with OCTA, enables dye-free visualization of normal and pathologic vascular development. |
| format | Article |
| id | doaj-art-bfac0acf80ff4fbb96bfb352f8757068 |
| institution | Directory of Open Access Journals |
| issn | 2296-2360 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| spelling | doaj-art-bfac0acf80ff4fbb96bfb352f87570682025-08-19T21:17:00ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-01-01910.3389/fped.2021.797684797684Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of PrematurityThanh-Tin P. Nguyen0Shuibin Ni1Shuibin Ni2Shanjida Khan3Shanjida Khan4Xiang Wei5Xiang Wei6Susan Ostmo7Michael F. Chiang8Michael F. Chiang9Yali Jia10Yali Jia11David Huang12David Huang13Yifan Jian14Yifan Jian15J. Peter Campbell16School of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesNational Eye Institute, National Institutes of Health, Bethesda, MD, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesDepartment of Biomedical Engineering, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesSchool of Medicine, Casey Eye Institute, Oregon Health and Science University, Portland, OR, United StatesRecent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the operating room of Oregon Health & Science University (OHSU) Hospital. In this observational study, we provide an overview of potential advantages of OCT-based disease assessment in ROP. We observed that next-generation OCT imaging (a) may be sufficient for objective diagnosis and zone/stage/plus disease categorization, (b) allows for minimally-invasive longitudinal monitoring of disease progression and post-treatment course, (c) provides three-dimensional mapping of the vitreoretinal interface, and (d) with OCTA, enables dye-free visualization of normal and pathologic vascular development.https://www.frontiersin.org/articles/10.3389/fped.2021.797684/fullretinopathy of prematuritypediatric retinaoptical coherence tomographyhandheld optical coherence tomographyoptical coherence tomography with angiography |
| spellingShingle | Thanh-Tin P. Nguyen Shuibin Ni Shuibin Ni Shanjida Khan Shanjida Khan Xiang Wei Xiang Wei Susan Ostmo Michael F. Chiang Michael F. Chiang Yali Jia Yali Jia David Huang David Huang Yifan Jian Yifan Jian J. Peter Campbell Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity retinopathy of prematurity pediatric retina optical coherence tomography handheld optical coherence tomography optical coherence tomography with angiography |
| title | Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity |
| title_full | Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity |
| title_fullStr | Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity |
| title_full_unstemmed | Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity |
| title_short | Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity |
| title_sort | advantages of widefield optical coherence tomography in the diagnosis of retinopathy of prematurity |
| topic | retinopathy of prematurity pediatric retina optical coherence tomography handheld optical coherence tomography optical coherence tomography with angiography |
| url | https://www.frontiersin.org/articles/10.3389/fped.2021.797684/full |
| work_keys_str_mv | AT thanhtinpnguyen advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT shuibinni advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT shuibinni advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT shanjidakhan advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT shanjidakhan advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT xiangwei advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT xiangwei advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT susanostmo advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT michaelfchiang advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT michaelfchiang advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT yalijia advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT yalijia advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT davidhuang advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT davidhuang advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT yifanjian advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT yifanjian advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity AT jpetercampbell advantagesofwidefieldopticalcoherencetomographyinthediagnosisofretinopathyofprematurity |