| 要約: | <p>This paper aims to investigate the relationship between the ratio of low-density lipoprotein cholesterol (LDL-C) to high-density lipoprotein cholesterol (HDL-C) and risk factors for acute ischemic stroke, and to investigate the effect of LDL-C/HDL-C on the 3-month outcome of acute ischemic stroke. Based on baseline characteristics and laboratory data on admission, 150 patients with non?cardiac acute ischemic stroke were divided into 2 groups (LDL-C/HDL-C ≤ 3 and LDL-C/HDL-C > 3). The outcome of 3 months after stroke was analyzed, and the risk factors were compared between 2 groups. There was significant difference in history of diabetes, history of coronary artery disease, history of smoking and atherosclerotic lesions between 2 groups (<em>P</em> < 0.05, for all). After using multifactor stepwise Logistic regression analysis, only the LDL-C/HDL-C ratio > 3 (<em>OR</em> = 1.781, 95%CI: 1.343-2.374;<em> P</em> = 0.001) and National Institute of Health Stroke Scale (NIHSS) score on admission (<em>OR</em> = 1.923, 95%CI: 1.232-5.944; <em>P</em> = 0.032) were significantly and independently predictive for 3-month outcome. Therefore, the ratio of LDL-C to HDL-C serves as a positive predictor of the 3-month clinical outcome of acute ischemic stroke.</p><p> </p><p><strong>doi:</strong> 10.3969/j.issn.1672-6731.2014.10.014</p>
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