Lifestyle and Clinical Predictors of Glial Cell Line-Derived Neurotrophic Factor Expression in Lumbosacral Stenosis-Related Ligamentum Flavum Degeneration
<b>Background/Objectives</b>: Degenerative spinal conditions, such as degenerative stenosis, have been linked to metabolic and lifestyle factors, including obesity, smoking, and diabetes. Glial cell line-derived neurotrophic factor (GDNF) plays a crucial role in neuroprotection, but its...
| Published in: | Biomedicines |
|---|---|
| Main Authors: | Dawid Sobański, Małgorzata Sobańska, Rafał Staszkiewicz, Damian Strojny, Werner Dammermann, Paweł Gogol, Weronika Wieczorek-Olcha, Artur Chwalba, Beniamin Oskar Grabarek |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/13/7/1530 |
Similar Items
Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential
by: Cristina Porcari, et al.
Published: (2025-06-01)
by: Cristina Porcari, et al.
Published: (2025-06-01)
Circulating Levels of Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Schizophrenia: a systematic review and meta-analysis
by: Omran Davarinejad, et al.
Published: (2025-01-01)
by: Omran Davarinejad, et al.
Published: (2025-01-01)
Modulation of Neurturin Expression by Lumbosacral Spinal Stenosis, Lifestyle Factors, and Glycemic Dysregulation
by: Małgorzata Sobańska, et al.
Published: (2025-05-01)
by: Małgorzata Sobańska, et al.
Published: (2025-05-01)
Research of relation between glial cell line-derived neurotrophic factor and digestive system tumor
by: WANG Xiao-juan, LI Xiao-li, JIN Zheng-xu, ZHANG De-kui
Published: (2020-07-01)
by: WANG Xiao-juan, LI Xiao-li, JIN Zheng-xu, ZHANG De-kui
Published: (2020-07-01)
Serum glial cell line-derived neurotrophic factor levels and impulsivity in heroin addiction: a cross-sectional, case-control study of 129 heroin addicts
by: Vahap Ozan Kotan, et al.
Published: (2018-04-01)
by: Vahap Ozan Kotan, et al.
Published: (2018-04-01)
Assessment of the Concentration of Transforming Growth Factor Beta 1–3 in Degenerated Intervertebral Discs of the Lumbosacral Region of the Spine
by: Rafał Staszkiewicz, et al.
Published: (2024-11-01)
by: Rafał Staszkiewicz, et al.
Published: (2024-11-01)
Cistanche tubulosa Protects Dopaminergic Neurons through Regulation of Appotosis and Glial Cell-derived Neurotrophic Factor: in Vivo and in Vitro
by: Qian Xu, et al.
Published: (2016-12-01)
by: Qian Xu, et al.
Published: (2016-12-01)
An emulsion electrospun nanofibrous scaffold loaded with glial cell line-derived neurotrophic factor for nerve regeneration
by: Holly N. Gregory, et al.
Published: (2025-04-01)
by: Holly N. Gregory, et al.
Published: (2025-04-01)
Brain-derived neurotrophic factor in intervertebral disc degeneration of the lumbosacral spine
by: Rafał Staszkiewicz, et al.
Published: (2023-01-01)
by: Rafał Staszkiewicz, et al.
Published: (2023-01-01)
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation
by: Kouminin Kanwore, et al.
Published: (2023-10-01)
by: Kouminin Kanwore, et al.
Published: (2023-10-01)
Intramuscular enteric glia persist in Hirschsprung disease and undergo neurogenesis in response to GDNF-NCAM1 signaling
by: Jessica L. Mueller, et al.
Published: (2025-09-01)
by: Jessica L. Mueller, et al.
Published: (2025-09-01)
The Influence of Neurotrophic Factors BDNF and GDNF Overexpression on the Functional State of Mice and Their Adaptation to Audiogenic Seizures
by: Angelina O. Kustova, et al.
Published: (2022-08-01)
by: Angelina O. Kustova, et al.
Published: (2022-08-01)
Human lumbosacral root and ligamentum flavum thicknesses: a magnetic resonance study
by: R. Khasawneh, et al.
Published: (2023-02-01)
by: R. Khasawneh, et al.
Published: (2023-02-01)
Multi-omics profiling of TGF-β isoforms and regulatory miRNAs in astrocytic tumors reveals TGF-β-3 as a prognostic biomarker
by: Klaudia Skóra, et al.
Published: (2025-06-01)
by: Klaudia Skóra, et al.
Published: (2025-06-01)
Assessment of addiction behavior and spermatogenesis in glial cell line-derived neurotrophic factor-treated cannabis-addicted rats: An experimental study
by: Rozhina Laleh, et al.
Published: (2025-04-01)
by: Rozhina Laleh, et al.
Published: (2025-04-01)
Postresuscitation Changes in the Expression of GlialDerived Neurotrophic Factor (GDNF): Association with Cerebellar Purkinje Cell Damage (An experimental study)
by: M. Sh. Avrushchenko, et al.
Published: (2014-10-01)
by: M. Sh. Avrushchenko, et al.
Published: (2014-10-01)
Ossification of the Ligamentum Flavum
by: Dong Ki Ahn, et al.
Published: (2014-02-01)
by: Dong Ki Ahn, et al.
Published: (2014-02-01)
Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy
by: Tuane Bazanella Sampaio, et al.
Published: (2017-01-01)
by: Tuane Bazanella Sampaio, et al.
Published: (2017-01-01)
Elemental imbalance and oxidative biomarker shifts in lumbar disc degeneration
by: Damian Strojny, et al.
Published: (2025-10-01)
by: Damian Strojny, et al.
Published: (2025-10-01)
The effect of high intensity interval swimming training on Glial cell line-derived neurotrophic factor and Rearranged during transfection (RET) gene expression in hippocampal tissue in rats with reserpine induced-Parkinson's disease
by: Sahar Abdolahi, et al.
Published: (2024-01-01)
by: Sahar Abdolahi, et al.
Published: (2024-01-01)
Impact of cigarette smoking on neurotrophic factors: insight to BDNF, GDNF, and NGF alterations
by: Behnoosh Miladpour, et al.
Published: (2025-06-01)
by: Behnoosh Miladpour, et al.
Published: (2025-06-01)
Revisiting the Role of Neurotrophic Factors in Inflammation
by: Lucas Morel, et al.
Published: (2020-04-01)
by: Lucas Morel, et al.
Published: (2020-04-01)
The Role of Metals in the Neuroregenerative Action of BDNF, GDNF, NGF and Other Neurotrophic Factors
by: Vincenzo Giuseppe Nicoletti, et al.
Published: (2022-07-01)
by: Vincenzo Giuseppe Nicoletti, et al.
Published: (2022-07-01)
Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis
by: Wesley M. Stansberry, et al.
Published: (2023-08-01)
by: Wesley M. Stansberry, et al.
Published: (2023-08-01)
The Impacts of Intervertebral Disc Degeneration of the Spine, Alcohol Consumption, Smoking Tobacco Products, and Glycemic Disorders on the Expression Profiles of Neurotrophins-3 and -4
by: Rafał Staszkiewicz, et al.
Published: (2024-02-01)
by: Rafał Staszkiewicz, et al.
Published: (2024-02-01)
Association between glial fibrillary acidic protein, glial-derived neurotrophic factor, and fatty acid-binding protein-2 at birth in the incidence of necrotizing enterocolitis in preterm infants
by: Dina Angelika, et al.
Published: (2022-10-01)
by: Dina Angelika, et al.
Published: (2022-10-01)
Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation
by: Shen Yujun, et al.
Published: (2012-11-01)
by: Shen Yujun, et al.
Published: (2012-11-01)
Pathogenesis of thoracic ossification of the ligamentum flavum
by: Chi Zhang, et al.
Published: (2024-10-01)
by: Chi Zhang, et al.
Published: (2024-10-01)
Ossification of the ligamentum flavum in the cervical spine
by: L Dewachter, et al.
Published: (2011-04-01)
by: L Dewachter, et al.
Published: (2011-04-01)
Hypericum perforatum chronic treatment affects cognitive parameters and brain neurotrophic factor levels
by: Samira S. Valvassori, et al.
Published: (2018-08-01)
by: Samira S. Valvassori, et al.
Published: (2018-08-01)
Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone
by: Madeha Ishag Adam, et al.
Published: (2023-01-01)
by: Madeha Ishag Adam, et al.
Published: (2023-01-01)
Level of glial cell derived neurotrophic factor in the blood plasma of rheumatoid arthritis patients and its relationship
with alexithymia
by: Yevhenii Shalkovskyi, et al.
Published: (2024-04-01)
by: Yevhenii Shalkovskyi, et al.
Published: (2024-04-01)
Lumbar Ligamentum Flavum Cyst: Case Report
by: Veysel Kaplanoğlu, et al.
Published: (2019-11-01)
by: Veysel Kaplanoğlu, et al.
Published: (2019-11-01)
Cervical myelopathy caused by ligamentum flavum ossification
by: Wellingson Silva Paiva, et al.
Published: (2012-01-01)
by: Wellingson Silva Paiva, et al.
Published: (2012-01-01)
Cellular and Molecular Mechanisms of Hypertrophy of Ligamentum Flavum
by: Prashanta Silwal, et al.
Published: (2024-10-01)
by: Prashanta Silwal, et al.
Published: (2024-10-01)
Response to: “Quantitative Histological Analysis of Ligamentum Flavum”
by: Idiris Altun
Published: (2018-04-01)
by: Idiris Altun
Published: (2018-04-01)
The Interplay Between Suicidal Behavior and Mental Disorders: Focusing on the Role of Glial Cells
by: Maya N. Abou Chahla
Published: (2025-06-01)
by: Maya N. Abou Chahla
Published: (2025-06-01)
Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese
by: Katriana A. Popichak, et al.
Published: (2018-11-01)
by: Katriana A. Popichak, et al.
Published: (2018-11-01)
The Effect of Internal and External Attention in Futsal Dribbling Skills on Serum Level of Glial Cell Line-Derived Neurotrophic Factor and Cognitive Function
by: Elham Sheibani, et al.
Published: (2023-09-01)
by: Elham Sheibani, et al.
Published: (2023-09-01)
Relationship between cognitive functions and serum neurotrophic factor levels in long-term hospitalized male patients with schizophrenia
by: Pan Jing, et al.
Published: (2025-07-01)
by: Pan Jing, et al.
Published: (2025-07-01)
Similar Items
-
Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential
by: Cristina Porcari, et al.
Published: (2025-06-01) -
Circulating Levels of Glial Cell Line-Derived Neurotrophic Factor (GDNF) in Schizophrenia: a systematic review and meta-analysis
by: Omran Davarinejad, et al.
Published: (2025-01-01) -
Modulation of Neurturin Expression by Lumbosacral Spinal Stenosis, Lifestyle Factors, and Glycemic Dysregulation
by: Małgorzata Sobańska, et al.
Published: (2025-05-01) -
Research of relation between glial cell line-derived neurotrophic factor and digestive system tumor
by: WANG Xiao-juan, LI Xiao-li, JIN Zheng-xu, ZHANG De-kui
Published: (2020-07-01) -
Serum glial cell line-derived neurotrophic factor levels and impulsivity in heroin addiction: a cross-sectional, case-control study of 129 heroin addicts
by: Vahap Ozan Kotan, et al.
Published: (2018-04-01)
