Characteristics and Validation Techniques for PCA-Based Gene-Expression Signatures

Background. Many gene-expression signatures exist for describing the biological state of profiled tumors. Principal Component Analysis (PCA) can be used to summarize a gene signature into a single score. Our hypothesis is that gene signatures can be validated when applied to new datasets, using inhe...

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Bibliographic Details
Published in:	International Journal of Genomics
Main Authors:	Anders E. Berglund, Eric A. Welsh, Steven A. Eschrich
Format:	Article
Language:	English
Published:	Wiley 2017-01-01
Online Access:	http://dx.doi.org/10.1155/2017/2354564

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