Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment

This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne and isotretinoin’s mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin and androgen signaling activate the kinase AKT and mechanistic target of rapamycin complex 1 (mTORC1). A Weste...

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Bibliographic Details
Published in:	Cells
Main Author:	Bodo C. Melnik
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Subjects:	acne apoptosis FoxO1 FoxO3 isotretinoin mTORC1
Online Access:	https://www.mdpi.com/2073-4409/12/22/2600

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