Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding

Ebola virus (EBOV) infection is highly lethal and results in severe febrile bleeding disorders that affect humans and non-human primates. One of the therapeutic approaches for treating EBOV infection focus largely on cocktails of monoclonal antibodies (mAbs) that bind to specific regions of the EBOV...

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Bibliographic Details
Published in:	Human Vaccines & Immunotherapeutics
Main Authors:	Daniel R. Ripoll, Daniel A. J. Mitchell, Lesley C. Dupuy, Anders Wallqvist, Connie Schmaljohn, Sidhartha Chaudhury
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-12-01
Subjects:	ebola glycoprotein dna vaccine ebola antibody epitope mapping ebolaviruses
Online Access:	http://dx.doi.org/10.1080/21645515.2017.1360454

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