Medico-legal aspect of amphetamine-related deaths

The subject of the work included 41 cases of death in which amphetamine was involved as the direct or indirect cause. Identification and determination of xenobiotics in blood samples collected from post-mortem cases were performed by high-performance liquid chromatography coupled with tandem mass sp...

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Bibliographic Details
Published in:Archives of Forensic Medicine and Criminology
Main Authors: Karol Kula, Sebastian Rojek, Martyna Maciów-Głąb, Paweł Kopacz, Małgorzata Kłys
Format: Article
Language:English
Published: Polish Society of Forensic Medicine and Criminology (PTMSiK) 2014-12-01
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Online Access:http://www.termedia.pl/Medico-legal-aspect-of-amphetamine-related-deaths,82,24174,1,1.html
Description
Summary:The subject of the work included 41 cases of death in which amphetamine was involved as the direct or indirect cause. Identification and determination of xenobiotics in blood samples collected from post-mortem cases were performed by high-performance liquid chromatography coupled with tandem mass spectrometry with electrospray ionisation (HPLC-ESI-MS-MS). Only for two cases was the cause of death amphetamine poisoning. In most of the investigated cases the death was caused by poisoning due to complex amphetamine and other psychoactive substances (e.g. opiates, benzodiazepines, cocaine). In other cases, multi-organ damage (fall from a height, traffic accident), a puncture wound and wound incised, drowning, or asphyxiation by hanging were reported. It can be explained as risky, murderous, or suicidal actions of people who were under the influence of amphetamines. The presented paper focuses on the interpretation of amphetamine concentration in blood samples from the perspective of direct or indirect cause of death.
ISSN:0324-8267
1689-1716