Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control

Reductive stress leads to the loss of disulfide bond formation and induces the unfolded protein response of the endoplasmic reticulum (UPRER), necessary to regain proteostasis in the compartment. Here we show that peroxide accumulation during reductive stress attenuates UPRER amplitude by altering t...

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發表在:	Cell Reports
Main Authors:	Shuvadeep Maity, Asher Rajkumar, Latika Matai, Ajay Bhat, Asmita Ghosh, Ganesh Agam, Simarjot Kaur, Niraj R. Bhatt, Arnab Mukhopadhyay, Shantanu Sengupta, Kausik Chakraborty
格式:	Article
語言:	英语
出版:	Elsevier 2016-07-01
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211124716307653