Application of polyethylene glycol 8000 as plasticizer for the development of ellagic acid and Eudragit® EPO based solid dispersions using hot melt extrusion.

Solid dispersion formation by Hot melt extrusion (HME) is a widely used formulation strategy to improve the solubility and bioavailability of poorly water-soluble drugs. Despite this, they are limited by various factors such as drug-excipient miscibility, poor stability, limited drug loading and ex...

Full description

Bibliographic Details

Published in:	Journal Africain de Technologie Pharmaceutique et Biopharmacie
Main Authors:	Isaie Nyamba, Alexis M W Nembot, Bavouma Charles Sombié, Hermine Zimé-Diawara, B. G. Josias Yaméogo, Anna Lechanteur, Christian Damblon, Rasmané Semdé, Brigitte Evrard
Format:	Article
Language:	English
Published:	Société Ouest Africaine de Pharmacie Galénique et Industrielle 2024-07-01
Subjects:	Ellagic acid, polymer, ternary solid dispersions, hot melt extrusion, plasticizer, and dissolution.
Online Access:	https://soapgi-jatpb.org/index.php/jatpb/article/view/179