A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging

A new Schiff base rhodamine 6G-indole-conjugated (RIC) probe with amine groups was synthesized for the highly sensitive and selective detection of Fe3+ ions. RIC showed selectivity for Fe3+ with minimal interference from 14 other metal ions. The detection limit was 40 nM. Density functional theory (...

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Bibliographic Details
Published in:Results in Chemistry
Main Authors: Bao-Long Hou, Wenyu Li, Ruirui Feng, Xiumei Yang, Jianli Liu, Cuiling Wang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Subjects:
Fluorescent probe
Rhodamine derivative
Fe3+ detection
Cellular imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625002115
Description
Summary:A new Schiff base rhodamine 6G-indole-conjugated (RIC) probe with amine groups was synthesized for the highly sensitive and selective detection of Fe3+ ions. RIC showed selectivity for Fe3+ with minimal interference from 14 other metal ions. The detection limit was 40 nM. Density functional theory (DFT) was used to predict the orbital electron distribution and molecular geometry of the RIC-Fe3+ complex. Moreover, confocal laser scanning microscopy was employed to confirm the effectiveness of RIC for detecting Fe3+ in living cells. Additionally, RIC proved effective in detecting Fe3+ in aqueous samples, with favorable relative recovery and standard deviations, thus offering a new method for Fe3+ detection in practical applications.
ISSN:2211-7156

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