Asymptotic Relative Efficiency of Parametric and Nonparametric Survival Estimators

The dominance of non- and semi-parametric methods in survival analysis is not without criticism. Several studies have highlighted the decrease in efficiency compared to parametric methods. We revisit the problem of Asymptotic Relative Efficiency (<inline-formula><math xmlns="http://www...

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Bibliographic Details
Published in:Stats
Main Author: Szilárd Nemes
Format: Article
Language:English
Published: MDPI AG 2023-10-01
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Online Access:https://www.mdpi.com/2571-905X/6/4/72
Description
Summary:The dominance of non- and semi-parametric methods in survival analysis is not without criticism. Several studies have highlighted the decrease in efficiency compared to parametric methods. We revisit the problem of Asymptotic Relative Efficiency (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>R</mi><mi>E</mi></mrow></semantics></math></inline-formula>) of the Kaplan–Meier survival estimator compared to parametric survival estimators. We begin by generalizing Miller’s approach and presenting a formula that enables the estimation (numerical or exact) of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>R</mi><mi>E</mi></mrow></semantics></math></inline-formula> for various survival distributions and types of censoring. We examine the effect of follow-up time and censoring on <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>R</mi><mi>E</mi></mrow></semantics></math></inline-formula>. The article concludes with a discussion about the reasons behind the lower and time-dependent <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>A</mi><mi>R</mi><mi>E</mi></mrow></semantics></math></inline-formula> of the Kaplan–Meier survival estimator.
ISSN:2571-905X