Mitochondrial Autoantibodies and the Role of Apoptosis in Pemphigus Vulgaris

Pemphigus vulgaris (PV) is an IgG autoantibody-mediated, potentially fatal mucocutaneous disease manifested by progressive non-healing erosions and blisters. Beyond acting to inhibit adhesion molecules, PVIgGs elicit a unique process of programmed cell death and detachment of epidermal keratinocytes...

Full description

Bibliographic Details
Published in:	Antibodies
Main Authors:	Dana M. Hutchison, Anna-Marie Hosking, Ellen M. Hong, Sergei A. Grando
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	pemphigus vulgaris apoptosis antimitochondrial autoantibodies
Online Access:	https://www.mdpi.com/2073-4468/11/3/55

Similar Items

Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report
by: Diane Lukito Setiawan, et al.
Published: (2025-07-01)

Oral pemphigus vulgaris in a pediatric patient
by: Anand R, et al.
Published: (2010-09-01)

Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris
by: Jing-pei Liang, et al.
Published: (2025-08-01)

Pemphigus Vulgaris as Oral Mucosal Ulcer Progressive to Skin Lesion:
by: SM Anwar Sadat, et al.
Published: (2014-02-01)

Therapeutic plasma exchange-A new dawn in the treatment of pemphigus vulgaris
by: Rajesh Kumar, et al.
Published: (2015-01-01)

Patient genetics shape the autoimmune response in the blistering skin disease pemphigus vulgaris
by: John Baker, et al.
Published: (2023-01-01)

Caspase Inhibition as a Possible Therapeutic Strategy for Pemphigus Vulgaris: A Systematic Review of Current Evidence
by: Sanna Huda, et al.
Published: (2022-02-01)

Phosphorylated p38 mitogen-activated kinase in patients with pemphigus vulgaris: a case–controlled study
by: Shereen A Sobeih, et al.
Published: (2020-01-01)

Novel use of dupilumab in pemphigus vulgaris and pemphigus foliaceus
by: Christina Jiang, BS, MS, et al.
Published: (2023-12-01)

Treatment of refractory pemphigus vulgaris with efgartigimod
by: Matthew Helm, MD, et al.
Published: (2025-07-01)

The cutaneous form of pemphigus vulgaris of the pemphigus chancre type: clinical and therapeutic implications
by: Natalia Welc, et al.
Published: (2024-02-01)

Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88
by: Luan C, et al.
Published: (2023-09-01)

A rare new presentation of pemphigus vulgaris
by: Nikoo Mozafari, et al.
Published: (2022-06-01)

Expression of HLA-G in the Skin of Patients with Pemphigus Vulgaris
by: Fathemeh Yari, et al.
Published: (2008-03-01)

Pemphigus Vulgaris in the Mouth and Esophageal Mucosa
by: Angelo Gualberto de Macedo, et al.
Published: (2018-06-01)

Subtype transition from pemphigus vulgaris to pemphigus foliaceus
by: Ty Gilkey, BS, et al.
Published: (2023-01-01)

A study of the correlation between acantholysis and apoptosis for the pathogenesis of pemphigus vulgaris
by: YU. V. Karacheva, et al.
Published: (2017-08-01)

Major autoantibodies in pemphigus: detection and clinical significance
by: WANG Qijun, ZHU Haiqin, PAN Meng
Published: (2022-10-01)

A case of umbilical pemphigus vulgaris
by: ZHENG Hang, et al.
Published: (2024-11-01)

Case report: Mounded and refractory keratoses (MARK), a novel presentation of pemphigus vulgaris
by: Stephanie T. Le, et al.
Published: (2023-01-01)

Pemphigus vulgaris and koebner phenomenon
by: Hulya Nazik, et al.
Published: (2019-06-01)

Cocaine-induced pemphigus vulgaris
by: Margit L.W. Juhasz, MD, MSc, et al.
Published: (2021-03-01)

Pemphigus vulgaris
by: Sandhya Tamgadge, et al.
Published: (2011-01-01)

Pemphigus vulgaris
by: Adriana Maria Porro, et al.
Published: (2019-07-01)

Oral pemphigus vulgaris: dentists take‐home message
by: Aya Al‐Harbawee, et al.
Published: (2021-07-01)

Evaluation of the possible association between acantholysis and anti‐desmogleins 1 and 3 values in pemphigus vulgaris and pemphigus foliaceus
by: Maryam Mobarakabadi, et al.
Published: (2019-12-01)

Pemphigus vulgaris and foliaceus localized to the nose: Report of 2 cases
by: Mohannad G. Safadi, BS, et al.
Published: (2021-09-01)

Autoantibodies other than anti-desmogleins in pemphigus vulgaris patients
by: Marwah Adly Saleh, et al.
Published: (2017-01-01)

Coexistance of Pemphigus Vulgaris and Psoriasis in a Middle Aged Man
by: Sara Saniee, et al.
Published: (2017-01-01)

Adverse effects of parenteral dexamethasone in the treatment of pemphigus vulgaris
by: Mohammad Jamal Uddin, et al.
Published: (2016-08-01)

Gut Microbiome Dysbiosis in Patients with Pemphigus and Correlation with Pathogenic Autoantibodies
by: Si-Zhe Li, et al.
Published: (2024-07-01)

An Updated Review of Pemphigus Diseases
by: Ali M. Malik, et al.
Published: (2021-10-01)

Therapeutic difficulties related to optimization of pemphigus vulgaris treatment
by: Szymon Leonik, et al.
Published: (2020-12-01)

Extensive keloid scarring in a patient with pemphigus vulgaris
by: Dorsaf Elinkichari, et al.
Published: (2022-10-01)

IgG reactivity to different desmoglein-3 ectodomains in pemphigus vulgaris: novel panels for assessing disease severity
by: Soheil Tavakolpour, et al.
Published: (2024-10-01)

Treatment of pemphigus vulgaris and pemphigus foliaceus: experience with 71 patients over a 20 year period Tratamento do pênfigo vulgar e pênfigo foliáceo: experiência com 71 pacientes no período de 20 anos
by: Nurimar C. FERNANDES, et al.
Published: (2001-02-01)

Clinical utility of dermatoscopy in identifying cutaneous myiasis complicating pemphigus vulgaris lesions
by: Mohammed Asif Qureshi, et al.
Published: (2024-06-01)

TARC/CCL17 reflects the severity of pemphigus (pemphigus vulgaris and pemphigus foliaceus) at the initial presentation
by: Tomoya Takegami, et al.
Published: (2024-09-01)

Cytokine profiles in the sera of Egyptian patients with oral pemphigus vulgaris
by: Hossam Eid, et al.
Published: (2015-11-01)

Anesthetic considerations in pemphigus vulgaris: Case series and review of literature
by: Abhishek Bansal, et al.
Published: (2012-01-01)