Ca(2+)-dependent regulation of the Ca(2+) concentration in the myometrium mitochondria. I. Trifluoperazine effects on mitochondria membranes polarization and [Ca(2+)](m)

Са2+-dependent regulation of Ca2+ exchange in mitochondria is carried out with participation of calmodulin. We have shown previously that calmodulin antagonists reduced the level of mitochondrial membrane polarization and induced increase of the ionized Са concentration in both the mitochondrial mat...

Full description

Bibliographic Details
Published in:	The Ukrainian Biochemical Journal
Main Authors:	L. G. Babich, S. G. Shlykov, A. M. Kushnarova, S. O. Kosterin
Format:	Article
Language:	English
Published:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2016-08-01
Subjects:	ATP Mg mitochondria myometrium trifluoperazine
Online Access:	http://ukrbiochemjournal.org/wp-content/uploads/2016/09/Babich_4_16.pdf

Similar Items

Сalix[4]arene chalcone amides effects on myometrium mitochondria
by: S. G. Shlykov, et al.
Published: (2019-05-01)

Ca(2+)/H(+)-exchange in myometrium mitochondria
by: O. V. Kolomiets, et al.
Published: (2014-06-01)

Calmodulin antagonists effect on Ca(2+) level in the mitochondria and cytoplasm of myometrium cells
by: S. G. Shlykov, et al.
Published: (2015-10-01)

Ca(2+)-dependent regulation of the Ca(2+) concentration in the myometrium mitochondria. II. Ca(2+) effects on mitochondria membranes polarization and [Ca(2+)](m)
by: L. G. Babich, et al.
Published: (2017-06-01)

Modulation of myometrium mitochondrial membrane potential by calmodulin antagonists
by: S. G. Shlykov, et al.
Published: (2014-02-01)

Ca ion transport in smooth muscle mitochondria
by: L. G. Babich, et al.
Published: (2014-12-01)

The relationship between the ionized Ca concentration and mitochondrial functions
by: L. G. Babich, et al.
Published: (2018-04-01)

Mean centering of ratio spectra and successive derivative ratio spectrophotometric methods for determination of isopropamide iodide, trifluoperazine hydrochloride and trifluoperazine oxidative degradate
by: Maha M. Abdelrahman, et al.
Published: (2016-09-01)

Comparing the Velocity of Haloperidol, Chlorpromazine, Trifluoperazine, and Promethazine in Sedating of Aggressive Patients
by: Sayed Ghafour Mousavi, et al.
Published: (2019-08-01)

Involvement of KАТР-channels of plasma and mitochondrial membranes in maintaining the contractive function of myometrium of non-pregnant rat uterus
by: O. V. Tsymbalyuk, et al.
Published: (2020-06-01)

Electrochemical potential of the inner mitochondrial membrane and Ca(2+) homeostasis of myometrium cells
by: Yu. V. Danylovych, et al.
Published: (2015-10-01)

Calix[4]arene С-956 as a selective inhibitor of Ca2+-pump of the plasma membrane and a modulator of the contractile function in the myometrium
by: Olga Tsymbalyuk, et al.
Published: (2024-09-01)

The therapeutic potential of trifluoperazine against ethanol and cold water stress-induced gastric lesions in rat
by: Mohammad Khoshnoud, et al.
Published: (2022-03-01)

Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux
by: Jyotsna Mishra, et al.
Published: (2025-05-01)

CALIX[4]ARENES С-715 AND С-772 AS INSTRUMENTS OF INFLUENCE ON Са2+-TRANSPORT AND BIOENERGETICS IN MYOMETRIAL MITOCHONDRIA
by: I.S. FORYS, et al.
Published: (2024-04-01)

Total Matrix Ca2+ Modulates Ca2+ Efflux via the Ca2+/H+ Exchanger in Cardiac Mitochondria
by: Gayathri K. Natarajan, et al.
Published: (2020-09-01)

Activation of glybenclamide-sensitive mitochondrial swelling under induction of cyclosporin of A-sensitive mitochondrial pore
by: O. B. Vadzyuk, et al.
Published: (2014-08-01)

A new affine inhibitor of sodium pump thiacalix[4]arene С-1193 increases the intracellular concentration of Ca ions and modifies myometrium contractility
by: Т. О. Veklich, et al.
Published: (2023-10-01)

Trifluoperazine and Its Analog Suppressed the Tumorigenicity of Non-Small Cell Lung Cancer Cell; Applicability of Antipsychotic Drugs to Lung Cancer Treatment
by: Joo Yeon Jeong, et al.
Published: (2022-04-01)

Regulation of ionized calcium concentration in mitochondria matrix in the absence of exogenous Са(2+)
by: A. V. Sylenko, et al.
Published: (2021-06-01)

Calix[4]arene С-956 selectively inhibits plasma membrane Са(2+),Mg(2+)-АТРase in myometrial cells
by: Т. O. Veklich, et al.
Published: (2018-10-01)

Participation of KАТР-channels of plasma and mitochondrial membranes in the regulation of mechanokinetics of rat myometrium spontaneous contractions
by: O. V. Tsymbalyuk, et al.
Published: (2022-10-01)

Transport of Ca<sup>2+</sup> and Ca<sup>2+</sup>-Dependent Permeability Transition in the Liver and Heart Mitochondria of Rats with Different Tolerance to Acute Hypoxia
by: Konstantin N. Belosludtsev, et al.
Published: (2020-01-01)

Measurement of antioxidant activity with trifluoperazine dihydrochloride radical cation
by: M.N. Asghar, et al.
Published: (2008-06-01)

Kinetic regularities of thiacalix[4]arene C-1087 inhibitory effect on the activity of Mg(2+)-dependent Ca(2+)-transporting ATP hydrolase in the plasma membrane of smooth muscle cells
by: Т. О. Veklich, et al.
Published: (2024-02-01)

Ca2+ induced Lipid Peroxidation Accentuates Aging in Rat Brain Mitochondria
by: Mohan Kumar B. S., et al.
Published: (2025-03-01)

Assessment of the histone mark-based epigenomic landscape in human myometrium at term pregnancy
by: San Pin Steve Wu, et al.
Published: (2025-06-01)

Nitrofurantoin inhibits contractions of myometrium isolated from pregnant and nonpregnant rats
by: Ebru Celik Kavak, et al.
Published: (2018-06-01)

Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer
by: Sandrina Körner, et al.
Published: (2022-08-01)

Sigma-1 receptor is involved in modification of ER-mitochondria proximity and Ca2+ homeostasis in cardiomyocytes
by: Hideaki Tagashira, et al.
Published: (2023-02-01)

Influence of Tl(+) on the Ca(2+) and Na(+) movement across rat neonatal cardiomyocytes and rat heart mitochondria membranes
by: S. M. Korotkov, et al.
Published: (2020-02-01)

Kinetics of inhibitory effect of calix[4]arene С-90 on activity of transporting plasma membrane Cа(2+),Mg(2+)-ATPase of smooth muscle cells
by: T. O. Veklich, et al.
Published: (2014-10-01)

The Adhesion GPCR VLGR1/ADGRV1 Regulates the Ca<sup>2+</sup> Homeostasis at Mitochondria-Associated ER Membranes
by: Jacek Krzysko, et al.
Published: (2022-09-01)

Insights into the role of PGF2α in canine periparturient myometrium
by: Carolin Jungmann, et al.
Published: (2024-05-01)

ATP as a signaling molecule
by: L. G. Babich, et al.
Published: (2024-06-01)

Thiacalix[4]arene chalcone amides effect on myometrium contraction
by: O. V. Tsymbalyuk, et al.
Published: (2024-08-01)

Investigating the role of CFTR in human and mouse myometrium
by: Clodagh Prendergast, et al.
Published: (2024-01-01)

Transcriptomics and proteomics reveal associations between myometrium and intrauterine adhesions
by: Xiaotong Xu, et al.
Published: (2025-04-01)

Ca2+-associated triphasic pH changes in mitochondria during brown adipocyte activation
by: Yanyan Hou, et al.
Published: (2017-08-01)

A bioprinted model of pregnant human uterine myometrium
by: Craig Ulrich, et al.
Published: (2025-10-01)