Cost-effectiveness of ticagrelor plus aspirin versus aspirin in acute ischaemic stroke or transient ischaemic attack: an economic evaluation of the THALES trial
Objective THALES demonstrated that ticagrelor plus aspirin reduced the risk of stroke or death but increased bleeding versus aspirin during the 30 days following a mild-to-moderate acute non-cardioembolic ischaemic stroke (AIS) or high-risk transient ischaemic attack (TIA). There are no cost-effecti...
| Published in: | BMJ Neurology Open |
|---|---|
| Main Authors: | Yongjun Wang, S Claiborne Johnston, Pierre Amarenco, Carl Mellström, Mario Ouwens, Scott R Evans, Ritika Jain, Stefan James, Hans Denison, Per Ladenvall, Carlos A Molina, Anders Himmelmann, Mikael Knutsson, Amarjeet Tank, Klas Rikner |
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-10-01
|
| Online Access: | https://neurologyopen.bmj.com/content/5/2/e000478.full |
Similar Items
Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
by: Yongjun Wang, et al.
by: Yongjun Wang, et al.
Prevalence of Aspirin and Clopidogrel Resistance in Patients with Recurrent Ischaemic Cerebrovascular Disease
by: Niyata Hananta Karunawan, et al.
Published: (2021-12-01)
by: Niyata Hananta Karunawan, et al.
Published: (2021-12-01)
Comparison of effectiveness of aspirin, clopidogrel and cilostazol monotherapy treatment in ischaemic stroke
by: Endarwati Tuti, et al.
Published: (2025-01-01)
by: Endarwati Tuti, et al.
Published: (2025-01-01)
Previous Antiplatelet Therapy on Ticagrelor-Aspirin and Clopidogrel-Aspirin Efficacy in Intracranial Artery Stenosis
by: Qin Xu, et al.
Published: (2025-09-01)
by: Qin Xu, et al.
Published: (2025-09-01)
Renal safety evaluation of aspirin plus edaravone in patients with ischaemic stroke: a retrospective cohort study
by: Kun Liu, et al.
Published: (2022-04-01)
by: Kun Liu, et al.
Published: (2022-04-01)
Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin
by: Hamzah Khan, et al.
Published: (2020-10-01)
by: Hamzah Khan, et al.
Published: (2020-10-01)
Aspirin or Ticagrelor in Staphylococcus aureus Infective Endocarditis: Where Do We Stand?
by: Kirsten Leeten, et al.
Published: (2021-10-01)
by: Kirsten Leeten, et al.
Published: (2021-10-01)
Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial
by: Thomas W. Johnson, et al.
Published: (2020-12-01)
by: Thomas W. Johnson, et al.
Published: (2020-12-01)
Comparison of Different Laboratory Tests to Identify “Aspirin Resistance” and Risk of Vascular Events among Ischaemic Stroke Patients: A Double-Blind Study
by: Narayanaswamy Venketasubramanian, et al.
Published: (2022-05-01)
by: Narayanaswamy Venketasubramanian, et al.
Published: (2022-05-01)
Development of a quality by design based eco-friendly RP-HPLC method for Ticagrelor and Aspirin
by: Shivani Jani, et al.
Published: (2025-06-01)
by: Shivani Jani, et al.
Published: (2025-06-01)
Secondary prevention medication persistence and prognosis of acute ischaemic stroke or transient ischaemic attack
by: Lei Zhang, et al.
Published: (2021-09-01)
by: Lei Zhang, et al.
Published: (2021-09-01)
Continuation versus discontinuation of aspirin-based antiplatelet therapy for perioperative bleeding and ischaemic events in adults undergoing neurosurgery: protocol for a systematic review and meta-analysis
by: Ruquan Han, et al.
Published: (2021-09-01)
by: Ruquan Han, et al.
Published: (2021-09-01)
Combined with ticagrelor, 50 mg aspirin daily can reduce bleeding events without increasing ischemic risk compared with 75–100 mg aspirin daily in coronary artery disease patients: insights from the TIFU (Ticagrelor in Fuwai Hospital) study
by: Jiannan Li, et al.
Published: (2020-08-01)
by: Jiannan Li, et al.
Published: (2020-08-01)
Pathogenesis of ischaemic and non-ischaemic heart diseases in rheumatoid arthritis
by: Zoltan Szekanecz, et al.
Published: (2020-02-01)
by: Zoltan Szekanecz, et al.
Published: (2020-02-01)
Rationale and Study Design to Assess the Efficacy and Safety of Minocycline in Patients with Moderate to Severe Acute Ischaemic Stroke (EMPHASIS)
by: Liping Liu, et al.
by: Liping Liu, et al.
TWILIGHT: A Randomized Trial of Ticagrelor Monotherapy Versus Ticagrelor Plus Aspirin Beginning at 3 Months in High-risk Patients Undergoing Percutaneous Coronary Intervention
by: Johny Nicolas, et al.
Published: (2020-05-01)
by: Johny Nicolas, et al.
Published: (2020-05-01)
Ticagrelor plus aspirin in patients with minor ischemic stroke and transient ischemic attack: a network meta-analysis
by: Mingxia Li, et al.
Published: (2023-08-01)
by: Mingxia Li, et al.
Published: (2023-08-01)
Abstract Number: LBA21 Platelet Function Assays for Aspirin and Ticagrelor are More Reliable When Compared with Clopidogrel
by: Farah Y Fourcand, et al.
Published: (2023-03-01)
by: Farah Y Fourcand, et al.
Published: (2023-03-01)
Ticagrelor Versus Clopidogrel or Aspirin in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Trials
by: Abdullah Faiz Zaihan, et al.
Published: (2026-01-01)
by: Abdullah Faiz Zaihan, et al.
Published: (2026-01-01)
Thales on Water
by: Ryszard Legutko
Published: (2017-10-01)
by: Ryszard Legutko
Published: (2017-10-01)
Nerve compression as an essential factor in causing ischaemic and post-ischaemic paraesthesiae
by: Eros Abrantes Erhart
Published: (1950-03-01)
by: Eros Abrantes Erhart
Published: (1950-03-01)
Body mass index affecting ticagrelor monotherapy vs. ticagrelor with aspirin in patients with acute coronary syndrome: A pre-specified sub-analysis of the TICO randomized trial
by: Byung Gyu Kim, et al.
Published: (2023-03-01)
by: Byung Gyu Kim, et al.
Published: (2023-03-01)
Platelet inhibition during ticagrelor monotherapy versus ticagrelor plus aspirin in patients with coronary artery disease (TEMPLATE study): study protocol for a randomised controlled trial
by: Sarah Baos, et al.
Published: (2017-11-01)
by: Sarah Baos, et al.
Published: (2017-11-01)
Pharmacodynamic effects of early aspirin withdrawal after percutaneous coronary intervention in patients with atrial fibrillation treated with ticagrelor or prasugrel
by: Mark A. Sammut, et al.
Published: (2025-12-01)
by: Mark A. Sammut, et al.
Published: (2025-12-01)
Ischaemic contracture of the hand
by: Balakrishnan G
Published: (2006-01-01)
by: Balakrishnan G
Published: (2006-01-01)
Ischaemic contracture of the hand
by: G. Balakrishnan
Published: (2006-01-01)
by: G. Balakrishnan
Published: (2006-01-01)
Revascularisation for Ischaemic Cardiomyopathy
by: Matthew E Li Kam Wa, et al.
Published: (2023-08-01)
by: Matthew E Li Kam Wa, et al.
Published: (2023-08-01)
Ischaemic Heart Disease
by: K R Mahajan
Published: (2013-04-01)
by: K R Mahajan
Published: (2013-04-01)
Ischaemic optic neuropathy.
by: Hayreh Sohan
Published: (2000-01-01)
by: Hayreh Sohan
Published: (2000-01-01)
Post-Ischaemic Immunological Response in the Brain: Targeting Microglia in Ischaemic Stroke Therapy
by: Charlotte Rawlinson, et al.
Published: (2020-03-01)
by: Charlotte Rawlinson, et al.
Published: (2020-03-01)
Aspirin Resistance
by: Khaled Mansour, et al.
Published: (2009-01-01)
by: Khaled Mansour, et al.
Published: (2009-01-01)
Preeclampsia and aspirin
by: Tae Gyu Ahn, et al.
Published: (2023-05-01)
by: Tae Gyu Ahn, et al.
Published: (2023-05-01)
Atherosclerosis and Aspirin
by: Piyarat Surapruk, et al.
Published: (2015-02-01)
by: Piyarat Surapruk, et al.
Published: (2015-02-01)
The Role of Cardiac MRI in the Management of Ventricular Arrhythmias in Ischaemic and Non-ischaemic Dilated Cardiomyopathy
by: Tom Nelson, et al.
Published: (2019-01-01)
by: Tom Nelson, et al.
Published: (2019-01-01)
Current Therapies for Neonatal Hypoxic–Ischaemic and Infection-Sensitised Hypoxic–Ischaemic Brain Damage
by: Konstantina Tetorou, et al.
Published: (2021-08-01)
by: Konstantina Tetorou, et al.
Published: (2021-08-01)
Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin
by: Chen J, et al.
Published: (2022-03-01)
by: Chen J, et al.
Published: (2022-03-01)
SHR2285, the first selectively oral FXIa inhibitor in China: Safety, tolerability, pharmacokinetics and pharmacodynamics combined with aspirin, clopidogrel or ticagrelor
by: Tingting Ma, et al.
Published: (2022-10-01)
by: Tingting Ma, et al.
Published: (2022-10-01)
Neglected Mendelian causes of stroke in adult Chinese patients who had an ischaemic stroke or transient ischaemic attack
by: Yongjun Wang, et al.
by: Yongjun Wang, et al.
Myocardial ischaemic pre-conditioning.
by: N K Vinod, et al.
Published: (2004-01-01)
by: N K Vinod, et al.
Published: (2004-01-01)
Prognostic Significance of Left Atrial Strain in Ischaemic and Non-ischaemic Dilated Cardiomyopathy: Multicentre Study
by: Fai Wang Fong, et al.
Published: (2024-01-01)
by: Fai Wang Fong, et al.
Published: (2024-01-01)
Similar Items
-
Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial
by: Yongjun Wang, et al. -
Prevalence of Aspirin and Clopidogrel Resistance in Patients with Recurrent Ischaemic Cerebrovascular Disease
by: Niyata Hananta Karunawan, et al.
Published: (2021-12-01) -
Comparison of effectiveness of aspirin, clopidogrel and cilostazol monotherapy treatment in ischaemic stroke
by: Endarwati Tuti, et al.
Published: (2025-01-01) -
Previous Antiplatelet Therapy on Ticagrelor-Aspirin and Clopidogrel-Aspirin Efficacy in Intracranial Artery Stenosis
by: Qin Xu, et al.
Published: (2025-09-01) -
Renal safety evaluation of aspirin plus edaravone in patients with ischaemic stroke: a retrospective cohort study
by: Kun Liu, et al.
Published: (2022-04-01)
