NOX1 and NOX2: Two enzymes that promote endothelial-to-mesenchymal transition induced by melanoma conditioned media

Tumor microenvironment plays an important role in melanoma progression. Recent studies reported endothelial cells (EC) are involved in endothelial-to-mesenchymal transition (EndMT). During this phenotypic switch, EC progressively lose their endothelial markers and acquire mesenchymal properties. Dep...

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Bibliographic Details
Published in:	Pharmacological Research
Main Authors:	Valentin Platel, Diane Lechevalier, Clara Bourreau, Sarah Renault, Ivana Šoborová, Caroline Jeannière, Ludovic Martin, Olivier Hérault, Isabelle Corre, Nicolas Clere
Format:	Article
Language:	English
Published:	Elsevier 2022-03-01
Subjects:	Endothelial cell Endothelial-to-mesenchymal transition Melanoma ROS NADPH oxidases
Online Access:	http://www.sciencedirect.com/science/article/pii/S1043661822000421

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