Comparison of early-stage changes of osteoarthritis in cartilage and subchondral bone between two different rat models
Osteoarthritis (OA) is a chronic degenerative joint disease and the major cause of joint pain and disability in the elderly. It is mainly characterized by articular cartilage degradation and subchondral bone remodeling. There are two main types of OA: natural occurring OA and secondary OA, mainly as...
| Published in: | PeerJ |
|---|---|
| Main Authors: | Yutao Yang, Peiran Li, Songsong Zhu, Ruiye Bi |
| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2020-04-01
|
| Subjects: | |
| Online Access: | https://peerj.com/articles/8934.pdf |
Similar Items
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
by: Yibao Wei, et al.
Published: (2024-06-01)
by: Yibao Wei, et al.
Published: (2024-06-01)
Comparison of bone and articular cartilage changes in osteoarthritis: a micro-computed tomography and histological study of surgically and chemically induced osteoarthritic rabbit models
by: Sharifah Zakiah Syed Sulaiman, et al.
Published: (2021-11-01)
by: Sharifah Zakiah Syed Sulaiman, et al.
Published: (2021-11-01)
The role of cells and signal pathways in subchondral bone in osteoarthritis
by: Pan Luo, et al.
Published: (2023-09-01)
by: Pan Luo, et al.
Published: (2023-09-01)
Comparative Analysis of Osteoarthritis Therapeutics: A Justification for Harnessing Retrospective Strategies via an Inverted Pyramid Model Approach
by: Quinn T. Ehlen, et al.
Published: (2024-10-01)
by: Quinn T. Ehlen, et al.
Published: (2024-10-01)
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats
by: Xiaoxia Hao, et al.
Published: (2022-04-01)
by: Xiaoxia Hao, et al.
Published: (2022-04-01)
Subchondral physiology and vasculo-mechanical factors in load transmission and osteoarthritis
by: Michael C. Beverly, et al.
Published: (2021-09-01)
by: Michael C. Beverly, et al.
Published: (2021-09-01)
Tribology of enzymatically degraded cartilage mimicking early osteoarthritis
by: Ke Ren, et al.
Published: (2023-05-01)
by: Ke Ren, et al.
Published: (2023-05-01)
The CREB1 inhibitor 666-15 maintains cartilage homeostasis and mitigates osteoarthritis progression
by: Ying Wang, et al.
Published: (2024-01-01)
by: Ying Wang, et al.
Published: (2024-01-01)
Do associations with hand OA vary by knee osteoarthritis phenotype? Cross-sectional data from the Multicenter Osteoarthritis Study
by: Michelle S. Yau, et al.
Published: (2023-03-01)
by: Michelle S. Yau, et al.
Published: (2023-03-01)
Biomarkers of Osteoarthritis—A Narrative Review on Causal Links with Metabolic Syndrome
by: Samuel James Lynskey, et al.
Published: (2023-03-01)
by: Samuel James Lynskey, et al.
Published: (2023-03-01)
Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model
by: Wonsae Lee, et al.
Published: (2024-01-01)
by: Wonsae Lee, et al.
Published: (2024-01-01)
New Drug Treatments for Osteoarthritis: What is on the Horizon
by: Fiona E. Watt, et al.
Published: (2017-03-01)
by: Fiona E. Watt, et al.
Published: (2017-03-01)
Soybean and avocado unsaponifiables: a review of their potential use in the treatment of osteoarthritis
by: Ana Sabucedo-Suárez, et al.
Published: (2025-01-01)
by: Ana Sabucedo-Suárez, et al.
Published: (2025-01-01)
Cross-Sectional and Longitudinal Associations of Comorbidities with Knee Symptoms and Radiographic Abnormalities of Osteoarthritis
by: Xiaoxi Li, et al.
Published: (2023-11-01)
by: Xiaoxi Li, et al.
Published: (2023-11-01)
Infrapatellar Fat Pad Modulates Osteoarthritis-Associated Cytokine and MMP Expression in Human Articular Chondrocytes
by: Ewa Wisniewska, et al.
Published: (2023-12-01)
by: Ewa Wisniewska, et al.
Published: (2023-12-01)
Lower Limb Kinematics in Individuals with Hip Osteoarthritis during Gait: A Focus on Adaptative Strategies and Interlimb Symmetry
by: Micaela Porta, et al.
Published: (2021-04-01)
by: Micaela Porta, et al.
Published: (2021-04-01)
Diamond Open Access in Norway 2017–2020
by: Jan Erik Frantsvåg
Published: (2022-03-01)
by: Jan Erik Frantsvåg
Published: (2022-03-01)
Biomechanics and pathomechanisms of osteoarthritis
by: Christian Egloff, et al.
Published: (2012-07-01)
by: Christian Egloff, et al.
Published: (2012-07-01)
CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis
by: Bin Li, et al.
Published: (2023-01-01)
by: Bin Li, et al.
Published: (2023-01-01)
Osteoarthritis: Mechanisms and Therapeutic Advances
by: Wei Liu, et al.
Published: (2025-08-01)
by: Wei Liu, et al.
Published: (2025-08-01)
Intra-Articular Drug Delivery for Osteoarthritis Treatment
by: Yifeng Cao, et al.
Published: (2021-12-01)
by: Yifeng Cao, et al.
Published: (2021-12-01)
Bloodborne Pathogens -- OSHA Standard 1910.1030
by: Carol J. Lehtola, et al.
Published: (2009-01-01)
by: Carol J. Lehtola, et al.
Published: (2009-01-01)
A Secondary Analysis: Comparison of Experimental Pain and Psychological Impact in Individuals with Carpometacarpal and Knee Osteoarthritis
by: Ordonez Diaz T, et al.
Published: (2023-12-01)
by: Ordonez Diaz T, et al.
Published: (2023-12-01)
Effectiveness of a telehealth physiotherapist-delivered intensive dietary weight loss program combined with exercise in people with knee osteoarthritis and overweight or obesity: study protocol for the POWER randomized controlled trial
by: Kim L. Bennell, et al.
Published: (2022-07-01)
by: Kim L. Bennell, et al.
Published: (2022-07-01)
Foot and ankle pain and risk of incident knee osteoarthritis and knee pain: Data from the Multicentre Osteoarthritis Study
by: Thomas A. Perry, et al.
Published: (2021-12-01)
by: Thomas A. Perry, et al.
Published: (2021-12-01)
Protective effects of equol on the cartilage and subchondral bone in ovariectomized rats with osteoarthritis
by: Shao-Hua Ping, et al.
Published: (2022-10-01)
by: Shao-Hua Ping, et al.
Published: (2022-10-01)
Depressive symptoms influence progression to total knee arthroplasty in patients with early knee osteoarthritis: Evidence from the Osteoarthritis Initiative database
by: Alessandro Bensa, et al.
Published: (2025-07-01)
by: Alessandro Bensa, et al.
Published: (2025-07-01)
A specific dual-mobility prosthesis design in trapeziometacarpal joint osteoarthritis
by: Giuseppe Rovere, et al.
Published: (2025-08-01)
by: Giuseppe Rovere, et al.
Published: (2025-08-01)
Relation between Q-angle and Clinical, Radiological, and Ultrasonographic findings in Primary Knee Osteoarthritis Patient
by: Mohamed Ismail Abdelkareem, et al.
Published: (2025-01-01)
by: Mohamed Ismail Abdelkareem, et al.
Published: (2025-01-01)
Bone marrow lesion coexisted with subchondral bone attrition and/or subchondral bone cyst is associated with knee pain in knee osteoarthritis regardless of cartilage lesion: the Bunkyo health study
by: Jun Tomura, et al.
Published: (2025-09-01)
by: Jun Tomura, et al.
Published: (2025-09-01)
Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation
by: Yang Zhou, et al.
Published: (2023-09-01)
by: Yang Zhou, et al.
Published: (2023-09-01)
Regenerative Effect of Mesenchymal Stem Cell on Cartilage Damage in a Porcine Model
by: Sheng-Chuan Lin, et al.
Published: (2023-06-01)
by: Sheng-Chuan Lin, et al.
Published: (2023-06-01)
Biomimetic Nanomaterials for Osteoarthritis Treatment: Targeting Cartilage, Subchondral Bone, and Synovium
by: Xiaoshan Gong, et al.
Published: (2024-12-01)
by: Xiaoshan Gong, et al.
Published: (2024-12-01)
YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis
by: Lina Zhang, et al.
Published: (2024-05-01)
by: Lina Zhang, et al.
Published: (2024-05-01)
THE ROLE POTENTIAL OF ARTIFICIAL INTELLIGENCE IN KNEE OSTEOARTHRITIS
by: Petya Subeva, et al.
Published: (2024-10-01)
by: Petya Subeva, et al.
Published: (2024-10-01)
Apigenin Inhibits the Progression of Osteoarthritis by Mediating Macrophage Polarization
by: Xueyan Ji, et al.
Published: (2023-03-01)
by: Xueyan Ji, et al.
Published: (2023-03-01)
Gut-joint axis: Oral Probiotic ameliorates Osteoarthritis
by: Uzma Amin, et al.
Published: (2024-01-01)
by: Uzma Amin, et al.
Published: (2024-01-01)
Cellular and Molecular Homeostatic Microenvironmental imbalances in Osteoarthritis and Rheumatoid Arthritis
by: Constantin Munteanu, et al.
Published: (2023-06-01)
by: Constantin Munteanu, et al.
Published: (2023-06-01)
Osteoimmunology in Osteoarthritis: Unraveling the Interplay of Immunity, Inflammation, and Joint Degeneration
by: Hu K, et al.
Published: (2025-03-01)
by: Hu K, et al.
Published: (2025-03-01)
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway
by: Yong Pang, et al.
Published: (2023-02-01)
by: Yong Pang, et al.
Published: (2023-02-01)
Similar Items
-
Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study
by: Yibao Wei, et al.
Published: (2024-06-01) -
Comparison of bone and articular cartilage changes in osteoarthritis: a micro-computed tomography and histological study of surgically and chemically induced osteoarthritic rabbit models
by: Sharifah Zakiah Syed Sulaiman, et al.
Published: (2021-11-01) -
The role of cells and signal pathways in subchondral bone in osteoarthritis
by: Pan Luo, et al.
Published: (2023-09-01) -
Comparative Analysis of Osteoarthritis Therapeutics: A Justification for Harnessing Retrospective Strategies via an Inverted Pyramid Model Approach
by: Quinn T. Ehlen, et al.
Published: (2024-10-01) -
Exercise modifies the disease-relevant gut microbial shifts in post-traumatic osteoarthritis rats
by: Xiaoxia Hao, et al.
Published: (2022-04-01)
