Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context
This review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa...
| Published in: | Marine Drugs |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-04-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/18/4/202 |
| _version_ | 1850411442214273024 |
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| author | Lauren M. Ashwood Raymond S. Norton Eivind A. B. Undheim David A. Hurwood Peter J. Prentis |
| author_facet | Lauren M. Ashwood Raymond S. Norton Eivind A. B. Undheim David A. Hurwood Peter J. Prentis |
| author_sort | Lauren M. Ashwood |
| collection | DOAJ |
| container_title | Marine Drugs |
| description | This review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa and Anthozoa). We highlight that the functional and ecological context of venom has implications for the temporal and spatial expression of protein and peptide toxins within class Anthozoa. Understanding the nuances in the regulation of venom arsenals has been made possible by recent advances in analytical technologies that allow characterisation of the spatial distributions of toxins. Furthermore, anthozoans are unique in that ecological roles can be assigned using tissue expression data, thereby circumventing some of the challenges related to pharmacological screening. |
| format | Article |
| id | doaj-art-cc26fe2e75b24ef0ab05cfcbb24dbe7d |
| institution | Directory of Open Access Journals |
| issn | 1660-3397 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-cc26fe2e75b24ef0ab05cfcbb24dbe7d2025-08-19T22:46:35ZengMDPI AGMarine Drugs1660-33972020-04-0118420210.3390/md18040202Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological ContextLauren M. Ashwood0Raymond S. Norton1Eivind A. B. Undheim2David A. Hurwood3Peter J. Prentis4School of Biology and Environmental Science, Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD 4000, AustraliaMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, AustraliaCentre for Biodiversity Dynamics, Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, NorwaySchool of Biology and Environmental Science, Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD 4000, AustraliaSchool of Biology and Environmental Science, Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD 4000, AustraliaThis review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa and Anthozoa). We highlight that the functional and ecological context of venom has implications for the temporal and spatial expression of protein and peptide toxins within class Anthozoa. Understanding the nuances in the regulation of venom arsenals has been made possible by recent advances in analytical technologies that allow characterisation of the spatial distributions of toxins. Furthermore, anthozoans are unique in that ecological roles can be assigned using tissue expression data, thereby circumventing some of the challenges related to pharmacological screening.https://www.mdpi.com/1660-3397/18/4/202CnidariaAnthozoaMedusozoavenomtoxinstranscriptomics |
| spellingShingle | Lauren M. Ashwood Raymond S. Norton Eivind A. B. Undheim David A. Hurwood Peter J. Prentis Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context Cnidaria Anthozoa Medusozoa venom toxins transcriptomics |
| title | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
| title_full | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
| title_fullStr | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
| title_full_unstemmed | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
| title_short | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
| title_sort | characterising functional venom profiles of anthozoans and medusozoans within their ecological context |
| topic | Cnidaria Anthozoa Medusozoa venom toxins transcriptomics |
| url | https://www.mdpi.com/1660-3397/18/4/202 |
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