Research progress on the effects of mineralocorticoid receptor on cardiovascular diseases
The mineralocorticoid receptor (MR) is a ligand-activated cytoplasmic receptor.Activation of MR in different cells can cause cardiovascular inflammation, oxidative stress, tissue remodeling ,and even function change the activity of ion channels resulting in incidence of arrhythmia through various me...
| Published in: | Jichu yixue yu linchuang |
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| Main Author: | |
| Format: | Article |
| Language: | Chinese |
| Published: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2022-08-01
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| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-8-1292.pdf |
| Summary: | The mineralocorticoid receptor (MR) is a ligand-activated cytoplasmic receptor.Activation of MR in different cells can cause cardiovascular inflammation, oxidative stress, tissue remodeling ,and even function change the activity of ion channels resulting in incidence of arrhythmia through various mechanisms.MR antagonists are effective medicine to treat hypertension,coronary heart disease,and heart failure. In addition, the role of MR in arrhythmia and pulmonary hypertension also provides new perspectives for future clinical medication. |
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| ISSN: | 1001-6325 |