Preparation, optimization and characterization of multiple unit microspheres containing kollidone SR

The present investigation described the influence of viscosity and drug: Polymer ratio on Hydrochlorothiazide release. Floating microspheres loaded with hydrochlorothiazide were prepared by Emulsion solvent evaporation method. The prepared microspheres were evaluated by micromeritics properties, in...

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Bibliographic Details
Published in:Journal of Pharmacy and Bioallied Sciences
Main Authors: Marvin I Patel, Ravi R Patel, Jayvadan K Patel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Subjects:
Hydrochlorthiazide
multiple unit microspheres
kollidone
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=5;spage=84;epage=85;aulast=Patel
Description
Summary:The present investigation described the influence of viscosity and drug: Polymer ratio on Hydrochlorothiazide release. Floating microspheres loaded with hydrochlorothiazide were prepared by Emulsion solvent evaporation method. The prepared microspheres were evaluated by micromeritics properties, in vitro drug release, floating ability and drug entrapment efficiency.
ISSN:0975-7406
0976-4879

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