Developing potent PROTACs tools for selective degradation of HDAC6 protein

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Protein & Cell
المؤلفون الرئيسيون:	Zixuan An, Wenxing Lv, Shang Su, Wei Wu, Yu Rao
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Oxford University Press 2019-01-01
الوصول للمادة أونلاين:	http://link.springer.com/article/10.1007/s13238-018-0602-z

مواد مشابهة

Correction to: Developing potent PROTACs tools for selective degradation of HDAC6 protein
حسب: Zixuan An, وآخرون
منشور في: (2019-02-01)

Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
حسب: Yuheng Jin, وآخرون
منشور في: (2025-03-01)

Development of highly potent and selective oncogenic KRASG12D PROTAC degraders
حسب: Yaqiu Mao, وآخرون
منشور في: (2025-12-01)

PROTAC‐Mediated HDAC7 Protein Degradation Unveils Its Deacetylase‐Independent Proinflammatory Function in Macrophages
حسب: Kailibinuer Kadier, وآخرون
منشور في: (2024-09-01)

Proteasomal Degradation of Zn-Dependent Hdacs: The E3-Ligases Implicated and the Designed Protacs That Enable Degradation
حسب: Laura Márquez-Cantudo, وآخرون
منشور في: (2021-09-01)

Recent Advances in the Development of Pro-PROTAC for Selective Protein Degradation
حسب: Fady Hakem, وآخرون
منشور في: (2025-09-01)

Targeted Degradation of Class 1 HDACs With PROTACs is Highly Effective at Inducing DLBCL Cell Death
حسب: Abdullah Alraddadi, وآخرون
منشور في: (2025-08-01)

mRNA PROTACs: engineering PROTACs for high‐efficiency targeted protein degradation
حسب: Xiaoqi Xue, وآخرون
منشور في: (2024-02-01)

Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy
حسب: Lu Liu, وآخرون
منشور في: (2024-12-01)

PROTACs improve selectivity for targeted proteins
حسب: Lihua Liu, وآخرون
منشور في: (2025-04-01)

PROTAC-induced protein structural dynamics in targeted protein degradation
حسب: Kingsley Y Wu, وآخرون
منشور في: (2025-02-01)

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs
حسب: Minoru Ishikawa, وآخرون
منشور في: (2020-04-01)

Targeted protein degradation in cancers: Orthodox PROTACs and beyond
حسب: Jin Li, وآخرون
منشور في: (2023-05-01)

PROTACs targeting epigenetic proteins
حسب: Chao Zhang, وآخرون
منشور في: (2023-11-01)

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
حسب: Si-Min Qi, وآخرون
منشور في: (2021-05-01)

Oligonucleotide-based PROTACs to Degrade RNA- and DNA-Binding Proteins
حسب: Céline N. Weller, وآخرون
منشور في: (2025-03-01)

From PROTAC to TPD: Advances and Opportunities in Targeted Protein Degradation
حسب: Siqi Wang, وآخرون
منشور في: (2024-01-01)

PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy
حسب: Jeremy M. Kelm, وآخرون
منشور في: (2023-03-01)

Linker-free PROTACs efficiently induce the degradation of oncoproteins
حسب: Jianchao Zhang, وآخرون
منشور في: (2025-05-01)

Beyond canonical PROTAC: biological targeted protein degradation (bioTPD)
حسب: Huifang Wang, وآخرون
منشور في: (2023-07-01)

PROTACs: Emerging Targeted Protein Degradation Approaches for Advanced Druggable Strategies
حسب: Nuwayo Ishimwe Sincere, وآخرون
منشور في: (2023-05-01)

Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor
حسب: Ilaria Cursaro, وآخرون
منشور في: (2025-08-01)

PROTAC Delivery Strategies for Overcoming Physicochemical Properties and Physiological Barriers in Targeted Protein Degradation
حسب: Endry Wahyu Syahputra, وآخرون
منشور في: (2025-04-01)

Design and synthesis of novel HDAC6 inhibitor dimer as HDAC6 degrader for cancer treatment by palladium catalysed dimerisation
حسب: Ching Lin, وآخرون
منشور في: (2025-12-01)

Characterization of PROTAC specificity and endogenous protein interactomes using ProtacID
حسب: Suman Shrestha, وآخرون
منشور في: (2025-08-01)

Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3
حسب: Jeremy Hall, وآخرون
منشور في: (2024-03-01)

Dual functionality of MDM2 in PROTACs expands the horizons of targeted protein degradation
حسب: Junyi Zhao, وآخرون
منشور في: (2025-08-01)

Modeling PROTAC degradation activity with machine learning
حسب: Stefano Ribes, وآخرون
منشور في: (2024-12-01)

Tubulin Resists Degradation by Cereblon-Recruiting PROTACs
حسب: Ivana Gasic, وآخرون
منشور في: (2020-04-01)

Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV
حسب: Lydia S. Newton, وآخرون
منشور في: (2025-02-01)

Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy
حسب: Zhimin Weng, وآخرون
منشور في: (2025-09-01)

Orthogonal validation of PROTAC mediated degradation of the integral membrane proteins EGFR and c-MET
حسب: Camilla Ruffilli, وآخرون
منشور في: (2025-01-01)

Versatile Split-and-Mix Liposome PROTAC Platform for Efficient Degradation of Target Protein In Vivo
حسب: Chunli Song, وآخرون
منشور في: (2024-07-01)

Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins
حسب: Alexander Chan, وآخرون
منشور في: (2024-07-01)

Targeted Protein Degradation to Overcome Resistance in Cancer Therapies: PROTAC and N-Degron Pathway
حسب: Hanbyeol Kim, وآخرون
منشور في: (2022-08-01)

Greener synthesis of a potent proteolysis targeting chimera (PROTAC) degrader of indoleamine-2, 3-dioxygenase 1 (hDOI1)
حسب: Emilie Buchs, وآخرون
منشور في: (2025-09-01)

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug
حسب: BoRa Lee, وآخرون
منشور في: (2023-12-01)

Recent Advances of Degradation Technologies Based on PROTAC Mechanism
حسب: Mingchao Xiao, وآخرون
منشور في: (2022-09-01)

PROTAC for Bruton’s tyrosine kinase degradation alleviates inflammation in autoimmune diseases
حسب: Can Zhu, وآخرون
منشور في: (2024-08-01)

PROTAC derivatization of natural products for target identification and drug discovery: Design of evodiamine-based PROTACs as novel REXO4 degraders
حسب: Shuqiang Chen, وآخرون
منشور في: (2024-09-01)