Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications & outcomes

Introduction: Reports about lateral lumbar or thoracic interbody fusion (LLIF) using expandable interbody spacers are sparse. Research question: To report our experience with the use of expandable spacers for LLIF. Material and methods: We reviewed all consecutive LLIF patients with use of an expand...

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Published in:Brain and Spine
Main Authors: Martin N. Stienen, Gregor Fischer, Linda Bättig, Anand Veeravagu, Benjamin Martens
Format: Article
Language:English
Published: Elsevier 2024-01-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772529424001267
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author Martin N. Stienen
Gregor Fischer
Linda Bättig
Anand Veeravagu
Benjamin Martens
author_facet Martin N. Stienen
Gregor Fischer
Linda Bättig
Anand Veeravagu
Benjamin Martens
author_sort Martin N. Stienen
collection DOAJ
container_title Brain and Spine
description Introduction: Reports about lateral lumbar or thoracic interbody fusion (LLIF) using expandable interbody spacers are sparse. Research question: To report our experience with the use of expandable spacers for LLIF. Material and methods: We reviewed all consecutive LLIF patients with use of an expandable titanium interbody implant (ELSA® Expandable Integrated LLIF Spacer, Globus Medical Inc, PA (USA)) between September 2018 and January 2024. Results: We identified 503 patients, in which we performed LLIF at 732 levels. In 63 patients (12.5%) and 70 levels (9.6%) an expandable spacer was used. The mean age was 61.4 years, 57.1% were females. LLIF was performed between T11/12 – L4/5 in the setting of fusion procedures (mono-/bisegmental (20; 28.6%), 3–7 segments (29; 41.4%); >7 segments (21; 30.0%)), of which 21 (33.3%), 20 (31.8%) and 22 (34.9%) were for traumatic, deformity/revision and other diagnoses. Surgery included release of the anterior longitudinal ligament in 30 cases (42.9%). Intraoperative adverse events (AEs) were noted in 2 (3.2%), postoperative AEs in 27 (42.9%) at discharge, 17 (27.0%) at 3 months and 14 (22.2%) at 12 months. Segmental sagittal Cobb angle changed from 1.3° (preoperative) to 13.0° at discharge (p < 0.001), 12.7° at 3 months (p < 0.001) and 13.3° at 12 months (p < 0.001). Functional outcome was excellent/good in 43 (68.3%; 5 missing) at 3 months and in 37 (58.7%; 10 missing) at 12 months. Discussion and conclusion: The use of LLIF with an expandable spacer was safe, promoted solid fusion and enabled powerful correction of sagittal segmental Cobb angle, which was maintained during follow-up.
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spelling doaj-art-cd5ec6a50e134790a379a3f8d15e894e2025-08-20T02:37:52ZengElsevierBrain and Spine2772-52942024-01-01410287010.1016/j.bas.2024.102870Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomesMartin N. Stienen0Gregor Fischer1Linda Bättig2Anand Veeravagu3Benjamin Martens4Spine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, Switzerland; Department of Neurosurgery, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, Switzerland; Corresponding author. Board-certified neurosurgeon (FMH), Fellow of the European Board of Neurological Surgeons (FEBNS), Senior attending, Department of Neurosurgery, Co-chair, Spine Center of Eastern Switzerland, Cantonal Hospital of St.Gallen &amp; Medical School of St.Gallen, Rorschacher Str. 95, CH-9007, St.Gallen, Switzerland.Spine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, Switzerland; Department of Neurosurgery, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, SwitzerlandSpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, Switzerland; Department of Neurosurgery, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, SwitzerlandDepartment of Neurosurgery, Stanford University, Stanford, CA, USASpine Center of Eastern Switzerland, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, Switzerland; Department of Orthopedic Surgery, Cantonal Hospital of St. Gallen &amp; Medical School of St. Gallen, St. Gallen, SwitzerlandIntroduction: Reports about lateral lumbar or thoracic interbody fusion (LLIF) using expandable interbody spacers are sparse. Research question: To report our experience with the use of expandable spacers for LLIF. Material and methods: We reviewed all consecutive LLIF patients with use of an expandable titanium interbody implant (ELSA® Expandable Integrated LLIF Spacer, Globus Medical Inc, PA (USA)) between September 2018 and January 2024. Results: We identified 503 patients, in which we performed LLIF at 732 levels. In 63 patients (12.5%) and 70 levels (9.6%) an expandable spacer was used. The mean age was 61.4 years, 57.1% were females. LLIF was performed between T11/12 – L4/5 in the setting of fusion procedures (mono-/bisegmental (20; 28.6%), 3–7 segments (29; 41.4%); >7 segments (21; 30.0%)), of which 21 (33.3%), 20 (31.8%) and 22 (34.9%) were for traumatic, deformity/revision and other diagnoses. Surgery included release of the anterior longitudinal ligament in 30 cases (42.9%). Intraoperative adverse events (AEs) were noted in 2 (3.2%), postoperative AEs in 27 (42.9%) at discharge, 17 (27.0%) at 3 months and 14 (22.2%) at 12 months. Segmental sagittal Cobb angle changed from 1.3° (preoperative) to 13.0° at discharge (p < 0.001), 12.7° at 3 months (p < 0.001) and 13.3° at 12 months (p < 0.001). Functional outcome was excellent/good in 43 (68.3%; 5 missing) at 3 months and in 37 (58.7%; 10 missing) at 12 months. Discussion and conclusion: The use of LLIF with an expandable spacer was safe, promoted solid fusion and enabled powerful correction of sagittal segmental Cobb angle, which was maintained during follow-up.http://www.sciencedirect.com/science/article/pii/S2772529424001267Lateral lumbar interbody fusionLateral thoracic interbody fusionExpandable spacerComplicationsSagittal parametersOutcome
spellingShingle Martin N. Stienen
Gregor Fischer
Linda Bättig
Anand Veeravagu
Benjamin Martens
Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
Lateral lumbar interbody fusion
Lateral thoracic interbody fusion
Expandable spacer
Complications
Sagittal parameters
Outcome
title Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
title_full Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
title_fullStr Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
title_full_unstemmed Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
title_short Minimally-invasive lateral thoracic and lumbar interbody fusion (LLIF) with expandable interbody cages – Considerations, complications &amp; outcomes
title_sort minimally invasive lateral thoracic and lumbar interbody fusion llif with expandable interbody cages considerations complications amp outcomes
topic Lateral lumbar interbody fusion
Lateral thoracic interbody fusion
Expandable spacer
Complications
Sagittal parameters
Outcome
url http://www.sciencedirect.com/science/article/pii/S2772529424001267
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