Targeting hedgehog-driven mechanisms of drug-resistant cancers

Due to the cellular plasticity that is inherent to cancer, the acquisition of resistance to therapy remains one of the biggest obstacles to patient care. In many patients, the surviving cancer cell subpopulation goes on to proliferate or metastasize, often as the result of dramatically altered cell...

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Bibliographic Details
Published in:	Frontiers in Molecular Biosciences
Main Authors:	Jade S. Miller, Natalie E. Bennett, Julie A. Rhoades
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	cancer chemotherapy resistance hedgehog Gli
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1286090/full

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