Tough surroundings make cancer tougher for immune cells to fight
The physical properties of the cells and proteins surrounding a tumor play a crucial role in determining the spread of the cancer. How they change cancer cells to suppress the immune response against them is an interesting question addressed in a recent study from Liu et al., which describes how inc...
| Published in: | Communications Biology |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-01-01
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| Online Access: | https://doi.org/10.1038/s42003-023-05756-4 |
| Summary: | The physical properties of the cells and proteins surrounding a tumor play a crucial role in determining the spread of the cancer. How they change cancer cells to suppress the immune response against them is an interesting question addressed in a recent study from Liu et al., which describes how increased stiffness of the tissue around the tumor decreases the amount of a protein—cyclic GMP-AMP synthase—in cancer cells, ultimately blocking the immune response to cancer. |
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| ISSN: | 2399-3642 |