Congenital Adrenal Hyperplasia– A Rare Cause of Central Precocious Puberty—A Case Report

The term ‘Precocious puberty’ refers to the appearance of pubertal signs at an earlier age than established standard. Precocious puberty may be central or peripheral. Central precocious puberty is caused by early maturation of hypothalamic-pituitary-gonadal axis. Peripheral precocious puberty is d...

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Bibliographic Details
Published in:Journal of Clinical and Diagnostic Research
Main Authors: JAYDEEP MAJUMDAR, ABHIJEET SHARAN, SARMISHTHA MUKHOPADHYAY, BHASKAR GHOSH, SARBANI SENGUPTA
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-11-01
Subjects:
adrenal gland hyperplasia
central precocity
hypothalamo-pituitary-gonadal axis
sex steroid
Online Access:https://jcdr.net/articles/PDF/10837/27330_CE(Ra1)_F(SS)_PF1(PB_AP)_PFA(MJ_GG).pdf
Description
Summary:The term ‘Precocious puberty’ refers to the appearance of pubertal signs at an earlier age than established standard. Precocious puberty may be central or peripheral. Central precocious puberty is caused by early maturation of hypothalamic-pituitary-gonadal axis. Peripheral precocious puberty is due to inappropriate secretion of sex steroid hormones from adrenal gland or gonad or from exogenous source and does not involve hypothalamo-pituitary-gonadal axis. We report a rare case where inspite of clinical and hormonal evidence of central precocious puberty ultimately an adrenal pathology was established in a six-year-old boy.
ISSN:2249-782X
0973-709X

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