Structure of a low-population intermediate state in the release of an enzyme product

Enzymes can increase the rate of biomolecular reactions by several orders of magnitude. Although the steps of substrate capture and product release are essential in the enzymatic process, complete atomic-level descriptions of these steps are difficult to obtain because of the transient nature of the...

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Bibliographic Details
Published in:	eLife
Main Authors:	Alfonso De Simone, Francesco A Aprile, Anne Dhulesia, Christopher M Dobson, Michele Vendruscolo
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2015-01-01
Subjects:	NMR spectroscopy residual dipolar coupling molecular dynamics simulation
Online Access:	https://elifesciences.org/articles/02777

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