SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

Reactive astrogliosis is a common pathological hallmark of CNS injury, infection, and neurodegeneration, where reactive astrocytes can be protective or detrimental to normal brain functions. Currently, the mechanisms regulating neuroprotective astrocytes and the extent of neuroprotection are poorly...

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Bibliographic Details
Published in:	eLife
Main Authors:	Surya Chandra Rao Thumu, Monika Jain, Sumitha Soman, Soumen Das, Vijaya Verma, Arnab Nandi, David H Gutmann, Balaji Jayaprakash, Deepak Nair, James P Clement, Swananda Marathe, Narendrakumar Ramanan
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2024-01-01
Subjects:	astrocytes reactive astrocytes astrogliosis SRF serum response factor neuroprotection
Online Access:	https://elifesciences.org/articles/95577

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