Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System

Oligonucleotide therapeutics such as miRNAs and siRNAs represent a class of molecules developed to modulate gene expression by interfering with ribonucleic acids (RNAs) and protein synthesis. These molecules are characterized by strong instability and easy degradation due to nuclease enzymes. To avo...

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Bibliographic Details
Published in:	Pharmaceutics
Main Authors:	Dalila Miele, Xin Xia, Laura Catenacci, Milena Sorrenti, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, John J. Rossi, Maria Cristina Bonferoni
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	nucleic acid delivery PLGA nanoparticles chitosan oleate siRNA polyplexes
Online Access:	https://www.mdpi.com/1999-4923/13/10/1716

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