Investigating novel Streptomyces bacteriophage endolysins as potential antimicrobial agents

ABSTRACT As antibiotic resistance has become a major global threat, the World Health Organization (WHO) has urgently called for alternative strategies for control of bacterial infections. Endolysin, a phage-encoded protein, can degrade bacterial peptidoglycan (PG) and disrupt bacterial growth. Accor...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Jindanuch Maneekul, Amanda Chiaha, Rachel Hughes, Faith Labry, Joshua Saito, Matthew Almendares, Brenda N. Banda, Leslie Lopez, Nyeomi McGaskey, Melizza Miranda, Jenil Rana, Brandon R. Zadeh, Lee E. Hughes
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-01-01
Subjects:	endolysin Streptomyces phage bioinformatics antimicrobial activity
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.01170-24