From Benchtop to Bedside: A Review of Oncolytic Virotherapy

Oncolytic viruses (OVs) demonstrate the ability to replicate selectively in cancer cells, resulting in antitumor effects by a variety of mechanisms, including direct cell lysis and indirect cell death through immune-mediate host responses. Although the mechanisms of action of OVs are still not fully...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Audrey H. Choi, Michael P. O’Leary, Yuman Fong, Nanhai G. Chen
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Subjects:
oncolytic viruses
immunotherapy
virotherapy
Online Access:http://www.mdpi.com/2227-9059/4/3/18

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