Precipitating Factors and Symptoms in Patients with Diabetic Ketoacidosis

• 出版年: Acta Clinica Croatica
• 主要な著者: Željka Dragila, Klara Ćosić, Ivana Grubešić, Srđan Čalošević, Krešimir Šolić, Tatjana Bačun
• フォーマット: 論文
• 言語: 英語
• 出版事項: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2023-01-01
• 主題: Diabetes mellitus; Diabetic ketoacidosis; Infection; Nausea; Vomiting
• オンライン･アクセス: https://hrcak.srce.hr/file/443376
• ISSN: 0353-9466; 1333-9451

The aim of the study was to determine the most common precipitating factors and symptoms of diabetic ketoacidosis and the possible difference according to age, gender and severity of diabetic ketoacidosis. Medical records from January 1, 2017 until December 31, 2019 were reviewed and patients diagnosed with diabetic ketoacidosis were selected. The study included 52 patients, median age 34 (interquartile range 21-56) years. There was no statistically significant difference between male and female gender. The severity of diabetic ketoacidosis was moderate in the majority of cases (65.4%; p=0.005). The most common precipitating factor was infection (61.7%). In patients with moderate diabetic ketoacidosis, respiratory infections were more common, while gastrointestinal infections were more common in severe diabetic ketoacidosis (33% and 25%, respectively; p=0.03). Nausea (median age 32 years; p=0.004) and vomiting (median age 31 years; p=0.01) were more common in younger age groups, while altered mental status was more common in the older age group (median age 61 years; p=0.001). Infection was the most common precipitating factor. The most common symptoms in younger age groups were nausea and vomiting, and altered mental status in the older age group.