Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish

Summary: LDLR, as the uptake receptor of low-density lipoprotein, plays a crucial role in lipid metabolism. However, the detailed mechanism by which LDLR affects hepatic triglyceride (TG) accumulation has rarely been reported. Here, we found that knockdown of LDLR effectively mitigated PA-induced TG...

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書目詳細資料
發表在:iScience
Main Authors: Xiufei Cao, Wei Fang, Xueshan Li, Xiuneng Wang, Kangsen Mai, Qinghui Ai
格式: Article
語言:英语
出版: Elsevier 2022-07-01
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2589004222009427