KCNJ2 Facilitates Clear Cell Renal Cell Carcinoma Progression and Glucose Metabolism

Conclusion: KCNJ2 plays a crucial role in ccRCC progression through affecting glucose metabolism and immune responses. Our findings reveal the functional role of KCNJ2 in promoting tumor progression and metabolic reprogramming in ccRCC, highlighting its therapeutic potential as a novel target for cc...

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Bibliographic Details
Published in:International Journal of Genomics
Main Authors: Qiyue Zhao, Zhengshu Wei, Guanglin Yang, Liwei Wei, Hao Chen, Zelin Cui, Naikai Liao, Min Qin, Jiwen Cheng
Format: Article
Language:English
Published: Wiley 2025-01-01
Online Access:http://dx.doi.org/10.1155/ijog/2210652
Description
Summary:Conclusion: KCNJ2 plays a crucial role in ccRCC progression through affecting glucose metabolism and immune responses. Our findings reveal the functional role of KCNJ2 in promoting tumor progression and metabolic reprogramming in ccRCC, highlighting its therapeutic potential as a novel target for ccRCC treatment. Further studies are essential to clarify the mechanisms by which KCNJ2 affects ccRCC biology and to evaluate its clinical relevance.
ISSN:2314-4378