Thyroid [123I]MIBG uptake in Parkinson’s disease and diabetes mellitus

Thyroid [123I]MIBG uptake is proposed as a tool for differentiating between Parkinson’s disease (PD) and diabetes mellitus (DM) on [123I]MIBG scintigraphies since both patient groups show decreased cardiac uptake. One study compared thyroid [123I]MIBG uptake in DM and PD patients and reported reduce...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:IBRO Neuroscience Reports
المؤلفون الرئيسيون: Tatyana D. Fedorova, Karoline Knudsen, Thorsten K. Rasmussen, Jacob Horsager, Adjmal Nahimi, Casper Skjærbæk, Eva Schaeffer, Daniela Berg, Astrid J. Terkelsen, Per Borghammer
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Elsevier 2023-06-01
الموضوعات:
Parkinson’s disease
Diabetes mellitus
MIBG
Thyroid gland
Scintigraphy
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S2667242123000234
الوصف
الملخص:Thyroid [123I]MIBG uptake is proposed as a tool for differentiating between Parkinson’s disease (PD) and diabetes mellitus (DM) on [123I]MIBG scintigraphies since both patient groups show decreased cardiac uptake. One study compared thyroid [123I]MIBG uptake in DM and PD patients and reported reduced [123I]MIBG uptake only in the PD group. Here, we investigated thyroid [123I]MIBG uptake in patients with PD and DM and found severely reduced thyroid [123I]MIBG uptake in DM. Larger studies are needed to substantiate whether DM patients are more or less likely to exhibit decreased thyroid MIBG uptake compared to controls and PD patients.
تدمد:2667-2421

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