TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis
Background Endometriosis (EMs) is a non-malignant gynecological disease, whose pathogenesis remains to be clarified. Recent studies have found that hypoxia induces epithelial-mesenchymal transition (EMT) as well as epigenetic modification in EMs. However, the relationship between EMT and demethylati...
| Published in: | PeerJ |
|---|---|
| Main Authors: | Jingni Wu, Xidie Li, Hongyan Huang, Xiaomeng Xia, Mengmeng Zhang, Xiaoling Fang |
| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2020-09-01
|
| Subjects: | |
| Online Access: | https://peerj.com/articles/9950.pdf |
Similar Items
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition
by: Kunyu Liu, et al.
Published: (2024-02-01)
by: Kunyu Liu, et al.
Published: (2024-02-01)
Targeting Mitochondrial ROS Production to Reverse the Epithelial-Mesenchymal Transition in Breast Cancer Cells
by: Elena Monti, et al.
Published: (2022-10-01)
by: Elena Monti, et al.
Published: (2022-10-01)
Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes
by: Vito Cela, et al.
Published: (2021-11-01)
by: Vito Cela, et al.
Published: (2021-11-01)
Unraveling the role of HIF2α in melanoma progression and epithelial–mesenchymal transition
by: Zhao Han, et al.
Published: (2025-07-01)
by: Zhao Han, et al.
Published: (2025-07-01)
LncRNAs as epigenetic regulators of epithelial to mesenchymal transition in pancreatic cancer
by: Yan Ma, et al.
Published: (2022-07-01)
by: Yan Ma, et al.
Published: (2022-07-01)
HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation
by: Jinjin Zhao, et al.
Published: (2024-10-01)
by: Jinjin Zhao, et al.
Published: (2024-10-01)
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1
by: Lu Liu, et al.
Published: (2025-04-01)
by: Lu Liu, et al.
Published: (2025-04-01)
Circulating miRNAs Related to Epithelial–Mesenchymal Transitions (EMT) as the New Molecular Markers in Endometriosis
by: Anna Zubrzycka, et al.
Published: (2021-08-01)
by: Anna Zubrzycka, et al.
Published: (2021-08-01)
The PKM2/HIF-1α Axis is Involved in the Pathogenesis of Endometriosis via TGF-β1 under Endometrial Polyps
by: Jianjuan Li, et al.
Published: (2024-12-01)
by: Jianjuan Li, et al.
Published: (2024-12-01)
TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy
by: Ji Ren, et al.
Published: (2024-12-01)
by: Ji Ren, et al.
Published: (2024-12-01)
Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid
by: Xinxin Guo, et al.
Published: (2024-04-01)
by: Xinxin Guo, et al.
Published: (2024-04-01)
Hypoxia-induced HIF-1α/VASN promotes bladder cancer progression
by: Qian-jin Zhang, et al.
Published: (2025-07-01)
by: Qian-jin Zhang, et al.
Published: (2025-07-01)
The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway
by: Liyun Yang, et al.
Published: (2023-09-01)
by: Liyun Yang, et al.
Published: (2023-09-01)
Cigarette smoke exposure promotes nasal polyp formation through down-regulating TET2
by: Peiqiang Liu, et al.
Published: (2025-11-01)
by: Peiqiang Liu, et al.
Published: (2025-11-01)
The Different Gene Expression Profile in the Eutopic and Ectopic Endometrium Sheds New Light on the Endometrial Seed in Endometriosis
by: Muhammad Assad Riaz, et al.
Published: (2024-06-01)
by: Muhammad Assad Riaz, et al.
Published: (2024-06-01)
Regulating the Expression of HIF-1α or lncRNA: Potential Directions for Cancer Therapy
by: Minghui Zhang, et al.
Published: (2022-09-01)
by: Minghui Zhang, et al.
Published: (2022-09-01)
Intersections of endocrine pathways and the epithelial mesenchymal transition in endometrial cancer
by: Julia H. Gelissen, et al.
Published: (2022-08-01)
by: Julia H. Gelissen, et al.
Published: (2022-08-01)
Effects of hypoxia stress on the milk synthesis in bovine mammary epithelial cells
by: Yanshan Jin, et al.
Published: (2025-03-01)
by: Yanshan Jin, et al.
Published: (2025-03-01)
H3K27me3-mediated epigenetic regulation of TET1 in the eutopic endometrium of women with endometriosis and infertility
by: Magdalena Adamczyk, et al.
Published: (2025-08-01)
by: Magdalena Adamczyk, et al.
Published: (2025-08-01)
Hyperbaric Oxygen (HBO) Reduce Expression of Hypoxia Inducible Factor-1 Alpha (HIF-1 alpha) and Endometriotic Tissue Size in Mice Model of Endometriosis
by: Syahrizal Dedy, et al.
Published: (2020-01-01)
by: Syahrizal Dedy, et al.
Published: (2020-01-01)
Features of epithelial-mesenchymal transition in ectopic endometrium in patients with extragenital endometriosis of various localizations. Observational study
by: Eugeniu Cazacu, et al.
Published: (2024-06-01)
by: Eugeniu Cazacu, et al.
Published: (2024-06-01)
Hypoxia/inflammation-induced upregulation of HIF-1α and C/EBPβ promotes nephroblastoma cell EMT by improving HOXA11-AS transcription
by: Shibo Zhu, et al.
Published: (2024-03-01)
by: Shibo Zhu, et al.
Published: (2024-03-01)
PPM1G Inhibits Epithelial–Mesenchymal Transition in Cholangiocarcinoma by Catalyzing TET1 Dephosphorylation for Destabilization to Impair Its Targeted Demethylation of the CLDN3 Promoter
by: Wenzheng Liu, et al.
Published: (2024-12-01)
by: Wenzheng Liu, et al.
Published: (2024-12-01)
Plasmid-borne tet(X3) and chromosome-borne tet(X6) in porcine Acinetobacter isolates
by: Jing Wang, et al.
Published: (2022-06-01)
by: Jing Wang, et al.
Published: (2022-06-01)
Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition
by: Wan Hua, et al.
Published: (2021-09-01)
by: Wan Hua, et al.
Published: (2021-09-01)
JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway
by: Qin Lin, et al.
Published: (2022-11-01)
by: Qin Lin, et al.
Published: (2022-11-01)
Tet2 loss and enhanced ciliogenesis suppress α-synuclein pathology
by: Emmanuel Quansah, et al.
Published: (2025-04-01)
by: Emmanuel Quansah, et al.
Published: (2025-04-01)
Predictive factors of endometriosis progression into ovarian cancer
by: Ján Varga, et al.
Published: (2022-01-01)
by: Ján Varga, et al.
Published: (2022-01-01)
Research models and mesenchymal/epithelial plasticity of osteosarcoma
by: Xiaobin Yu, et al.
Published: (2021-05-01)
by: Xiaobin Yu, et al.
Published: (2021-05-01)
Hypoxia-Inducible Factor 1 and Mitochondria: An Intimate Connection
by: Xiaochen Huang, et al.
Published: (2022-12-01)
by: Xiaochen Huang, et al.
Published: (2022-12-01)
Role of Digoxin in Preventing Cigarette Smoke-Induced COPD via HIF-1α Inhibition in a Mouse Model
by: Zhang K, et al.
Published: (2025-05-01)
by: Zhang K, et al.
Published: (2025-05-01)
HIF-1α Modulates Core Metabolism and Virus Replication in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus
by: Dorothea R. Morris, et al.
Published: (2020-09-01)
by: Dorothea R. Morris, et al.
Published: (2020-09-01)
Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum
by: Priyanka Chakraborty, et al.
Published: (2020-03-01)
by: Priyanka Chakraborty, et al.
Published: (2020-03-01)
Epithelial fusion is mediated by a partial epithelial–mesenchymal transition
by: Varsha N. Tamilkumar, et al.
Published: (2025-09-01)
by: Varsha N. Tamilkumar, et al.
Published: (2025-09-01)
D-chiro-inositol effectively counteracts endometriosis in a mouse model
by: Martina Placidi, et al.
Published: (2025-04-01)
by: Martina Placidi, et al.
Published: (2025-04-01)
Epithelial-to-mesenchymal plasticity harnesses endocytic circuitries
by: Giorgio eScita, et al.
Published: (2015-02-01)
by: Giorgio eScita, et al.
Published: (2015-02-01)
Epithelial to Mesenchymal Transition History: From Embryonic Development to Cancers
by: Camille Lachat, et al.
Published: (2021-05-01)
by: Camille Lachat, et al.
Published: (2021-05-01)
The Linkage between Breast Cancer, Hypoxia, and Adipose Tissue
by: Linda K. Rausch, et al.
Published: (2017-09-01)
by: Linda K. Rausch, et al.
Published: (2017-09-01)
Vitamin D receptor loss promotes endometrial fibrosis via autophagy-mediated epithelial–mesenchymal transition
by: Hongtao Zhu, et al.
Published: (2026-01-01)
by: Hongtao Zhu, et al.
Published: (2026-01-01)
HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes
by: Hongchen Li, et al.
Published: (2025-06-01)
by: Hongchen Li, et al.
Published: (2025-06-01)
Similar Items
-
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition
by: Kunyu Liu, et al.
Published: (2024-02-01) -
Targeting Mitochondrial ROS Production to Reverse the Epithelial-Mesenchymal Transition in Breast Cancer Cells
by: Elena Monti, et al.
Published: (2022-10-01) -
Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes
by: Vito Cela, et al.
Published: (2021-11-01) -
Unraveling the role of HIF2α in melanoma progression and epithelial–mesenchymal transition
by: Zhao Han, et al.
Published: (2025-07-01) -
LncRNAs as epigenetic regulators of epithelial to mesenchymal transition in pancreatic cancer
by: Yan Ma, et al.
Published: (2022-07-01)
