Prophylactic infusion of allogeneic double-negative T cells as immune modulators to prevent relapse in high-risk AML patients post-Allo-HSCT: a phase I trial

Abstract Relapse remains a major challenge for high-risk acute myeloid leukemia (AML) patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). In our first-in-human Phase I trial (ChiCTR-1900022795), we have demonstrated that third-party donor-derived double-negative T cell...

書誌詳細
出版年:	Experimental Hematology & Oncology
主要な著者:	Guangyu Sun, Xingchi Chen, Tianzhong Pan, Kaidi Song, Haicun Xie, Meijuan Tu, Xiang Wan, Wen Yao, Yaxin Cheng, Ziwei Zhou, Dongyao Wang, Yongsheng Han, Baolin Tang, Liming Yang, Xiaoyu Zhu
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-07-01
主題:	Double negative T cell Acute myeloid leukemia Allogeneic hematopoietic stem cell transplantation Relapse Adoptive cellular therapy Immune modulator
オンライン･アクセス:	https://doi.org/10.1186/s40164-025-00680-1

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